Trenaxa MF Tablet (6'S)

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₹264.00

Strip of 6 Tablet

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Trenaxa MF Tablet is a combination medicine used to treat heavy menstrual bleeding and menstrual pain. It prevents the breakdown of blood clots to control excessive bleeding during periods. It also blocks the production of certain chemical messengers that cause pain and inflammation.


You can take Trenaxa MF Tablet at any time of day, with food, but it is best to take it at the same time each day. It should be taken on first day of the periods to get the most benefit. Keep taking it for as long as advised by your doctor.  Take this medicine in the dose and duration advised by the doctor and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. Inform your doctor if you do not observe any change in periods even after 3 consecutive periods.


The most common side effects of this medicine include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle or joint) pain. It may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.


Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine. It is advised to avoid alcohol while taking this medicine.



Basic Information

Mechanism Of Action

Tranexamic acid is a synthetic derivative of the amino acid lysine and binds the 5 lysine binding sites on plasminogen. This inhibits plasmin formation and displaces plasminogen from the fibrin surface. It may also directly inhibit plasmin and partially inhibit fibrinogenolysis at higher concentrations Mefenamic acid binds the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase. As these receptors have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity, the symptoms of pain are temporarily reduced

Pharmacokinets

Tranexamic acid 1 g was given intravenously to three healthy volunteers. Plasma concentrations decayed in three monoexponential phases. Most elimination took place during the first eight hours, giving an apparent elimination half-life of approximately two hours. Plasma clearance ranged between 110-116 ml/min. Mefenamic acid pharmacokinetics have not been studied in patients with hepatic dysfunction. As hepatic metabolism is a significant pathway of mefenamic acid elimination, patients with acute and chronic hepatic disease may require reduced doses of Ponstel compared to patients with normal hepatic function

Side Effects

Nausea

Vomiting

Heartburn

Indigestion

Diarrhea

Loss of appetite

Nasal congestion (stuffy nose)

Headache

Tiredness

Musculoskeletal (bone, muscle or joint) pain

Anemia (low number of red blood cells)

Stomach pain

Sinus pain

Sinus inflammation


Contra Indications

increased risk of blood clotting. fluid accumulation in the brain. a clot in the small veins that carry blood to or from the retina of the eye. a heart attack. acute blood clot in a blood vessel supplying the lungs. heart valve disease. increased risk of bleeding due to clotting disorder. an increased risk of bleeding. high blood pressure. chronic heart failure. abnormal bleeding in the brain resulting in damage to brain tissue, called a hemorrhagic stroke. an ulcer from too much stomach acid.

Pregnancy Related Information

Trenaxa MF Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Trenaxa MF Tablet.


Breast Feeding Related Information

Trenaxa MF Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Tranexamic acid (sometimes shortened to txa) is a medicine that controls bleeding. It helps your blood to clot and is used for nosebleeds and heavy periods. If you're having a tooth taken out, using tranexamic acid mouthwash can help stop bleeding Mefenamic acid is used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period). Mefenamic acid is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation

Interactions

Tranexamic acid (sometimes shortened to txa) is a medicine that controls bleeding. It helps your blood to clot and is used for nosebleeds and heavy periods. If you're having a tooth taken out, using tranexamic acid mouthwash can help stop bleeding Mefenamic acid is used to relieve mild to moderate pain, including menstrual pain (pain that happens before or during a menstrual period). Mefenamic acid is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation

Typical Dosage

 Swallow it as a whole. Do not chew, crush or break it. Trenaxa MF Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Trenaxa MF Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Trenaxa MF Tablet helps relieve menstrual pain and abnormally heavy menstrual bleeding.

Your doctor will prescribe the lowest effective dose for the shortest possible time necessary to relieve your symptoms.

Take it with food to avoid an upset stomach.

Take it on the first day of a heavy period. Taking it before or after will not have any benefit.

Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive menstrual periods.

Inform your doctor if you have a history of kidney or liver disease

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trenaxa MF Tablet is to be taken with food.


FAQs

Q. What is Trenaxa MF Tablet?

Trenaxa MF Tablet is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. This medication is used to treat pain and is used to treat heavy bleeding during menstrual cycle (monthly periods) in women.

Q. Are there any specific contraindications associated with the use of Trenaxa MF Tablet?

Yes, it is considered to be harmful for patients with severe kidney failure, active intravascular clotting (obstruction in the blood flow due to blood clots), and color vision disorders.

Q. What is the recommended storage condition for Trenaxa MF Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.