Manufacturer: Novo Nordisk India Pvt Ltd
Salt Composition : Insulin Degludec(100IU)
Tresiba 100 Units/ml Penfill (3ml Each) can be prescribed by itself or along with a fast-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. You should use this medicine regularly as per the dose advised to get the most benefit. It is usually taken once daily at the same time every day. However, on occasions when administration at the same time of the day is not possible, it may be taken at a different time of the day. Always ensure that there is a minimum gap of 8 hours between doses. If you stop taking it your blood sugar levels may rise very high and put you at risk of serious complications. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine is low blood sugar levels (hypoglycemia). To prevent hypoglycemia, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include injection site reactions like redness, swelling, or hard lumps (lipohypertrophy). Some people may also gain weight while taking insulin.
Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver, or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor before using it.
Tresiba 100 Units/ml Penfill (3ml Each) is a long-acting insulin that provides consistent, all-day sugar control. It works like your body's natural insulin. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
Insulin degludec is given as a subcutaneous injection and forms a depot of soluble multihexamers [19S]. Insulin is then slowly absorbed into the circulation. The duration of action is over 42 hours and the half-life is over 25 hours. Steady state takes 2–3 days to reach [20S].
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tresiba
Hypoglycemia (low blood glucose level)
Injection site reactions (pain, swelling, redness)
Insulin degludec/liraglutide is contraindicated in patients with hypersensitivity to insulin degludec, liraglutide, or any component of the formulation. Insulin degludec/liraglutide is contraindicated during episodes of hypoglycemia.
Tresiba 100 Units/ml Penfill (3ml Each) is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is unsafe to consume alcohol with Tresiba 100 Units/ml Penfill (3ml Each).
Tresiba 100 Units/ml Penfill (3ml Each) is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Insulin degludec is indicated to improve glycemic control in patients 1 year of age and older with diabetes mellitus. Insulin is a natural hormone produced by beta cells of the pancreas.
The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Dabrafenib. The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Danazol. The risk or severity of hypoglycemia can be increased when Insulin degludec is combined with Dapagliflozin.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Tresiba 100 Units/ml Penfill (3ml Each) take it as soon as you remember. Do not take two doses of Tresiba 100 Units/ml Penfill (3ml Each) within 8 hours of each other.
Consult a doctor before taking any medicines.
This medicine is injected under the skin. It needs to be injected once daily, at the same time every day.
Injection below the skin of the abdomen results in faster absorption than other injection sites.
Injection sites must be rotated to prevent hard lumps from developing at one site.
Do not use if the preparation is no longer clear and colorless or if it contains particles.
Hypoglycemia (low blood sugar level) is a common side effect. Always carry some sugary food or fruit juice with you so that you can take it when you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
Opened vials/cartridge stay good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator (2°C–8°C).
Your doctor or nurse will guide you how to use this medicine.
Q. What is Tresiba 100 Units/ml Penfill (3ml Each)?
Tresiba 100 Units/ml Penfill (3ml Each) is an ultra long-acting type of insulin used to control high blood sugar in adults and children (as young as 1 year of age) with type 1 and type 2 diabetes mellitus. Tresiba 100 Units/ml Penfill (3ml Each) works like the insulin that is normally produced by the body and helps move sugar from the blood into other body tissues where it is used for energy production. Also, it stops the liver from producing more sugar and this helps to normalize the blood sugar levels.
Q. Are Insulin glargine and Tresiba 100 Units/ml Penfill (3ml Each) the same?
Both insulin glargine and Tresiba 100 Units/ml Penfill (3ml Each) are man-made versions of human insulin, but they are different in some aspects. On one hand, insulin glargine is a long-acting insulin that helps to maintain adequate blood sugar control for an entire day, although it cannot be combined with any other type of insulin. Whereas, on the other hand, Tresiba 100 Units/ml Penfill (3ml Each) is an ultra long-acting insulin that helps control blood sugar levels for more than a day and can be safely combined with other types of insulin (e.g., fast-acting insulin).
Q. Is Tresiba 100 Units/ml Penfill (3ml Each) better than Insulin Detemir?
Both Tresiba 100 Units/ml Penfill (3ml Each) and Insulin Detemir are long-acting insulins with almost similar effectiveness and safety. The only difference is that Tresiba 100 Units/ml Penfill (3ml Each) has the longest duration of action (more than 40 hours) and this helps to maintain steady blood sugar levels throughout this duration. Some studies have reported that Tresiba 100 Units/ml Penfill (3ml Each) may have a slightly lesser risk of hypoglycemia.
Q. Can Tresiba 100 Units/ml Penfill (3ml Each) cause weight gain?
Yes, Tresiba 100 Units/ml Penfill (3ml Each) may cause weight gain in some patients. This may be due to the anabolic effect of insulin which promotes the storage of glucose and fat.
