Tretiome 20mg Tablet (1'S)

Manufacturer: Jenome Biophar Pvt Ltd

Salt Composition : Tretinoin(20mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Tretiome 20mg Tablet belongs to a group of medicines called retinoids, which are similar to vitamin A. It is used to treat a type of blood problem called acute promyelocytic leukaemia. It works by slowing the growth of certain types of diseased blood cells.


Tretiome 20mg Tablet works by slowing the growth of certain types of diseased blood cells. It should be taken with food, preferably at the same time, each day, to avoid a missed dose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase side effects.


The most common side effects include headache, fever, dry skin and rash. They are not usually serious and often disappear after getting used to the cream but if they bother you or do not go away, tell your doctor. You may need to apply smaller amounts or use it less often. Serious side effects are rare.


Tretiome 20mg Tablet may make you more sensitive to sunlight so you should limit exposure to the sun if possible. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips, and eyes. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning to get pregnant.



Basic Information

Mechanism Of Action

Tretinoin promotes cornified cell detachment and enhances shedding. Tretinoin increases mitotic activity, thereby increasing loosely-adherent corneocytes turnover. By doing so, the comedo contents can be expelled, with a reduction of microcomedo precursor lesion of acne vulgaris

Pharmacokinets

The principal mechanisms proposed to explain the increased disappearance of tretinoin from plasma include: (i) decreased intestinal absorption; (ii) enhanced enzymatic catabolism; and (iii) the induction of cytoplasmic retinoic acid binding proteins (CRABP), which leads to increased drug sequestration

Side Effects

Headache

Fever

Bone pain

Rash

Visual impairment

Hair loss

Increased sweating

Mucosal inflammation

Erythema (skin redness)

Skin irritation

Dry skin

Dry lips

Pale red skin

Increased sensitivity to light


Contra Indications

Hypersensitivity to the drug, drug class, or drug formulation components.

Caution if hypersensitivity to fish products (0.05% gel, 0.05% lotion forms)

Caution if sunburn.

Caution if photosensitivity.

Caution if eczema.

Caution if pregnancy 1st trimester

Pregnancy Related Information

Tretiome 20mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Tretiome 20mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Tretiome 20mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Tretinoin is used to treat acne or other skin diseases as determined by your doctor. It works partly by keeping skin pores clear. One of the tretinoin creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by the damaging rays of the sun.

Interactions

Aminolevulinic acid.

Aminolevulinic acid topical.

Benzoyl peroxide.

Isotretinoin.

Methoxsalen.

Methyl aminolevulinate topical.

Porfimer.

Resorcinol.


Typical Dosage

Swallow it as a whole. Do not chew, crush or break it. Tretiome 20mg Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Tretiome 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

Tretiome 20mg Tablet helps in the treatment of blood cancer.

Take it with or just after food.

This medicine is usually taken until there is no sign of cancer (you are in remission) or for a maximum of 90 days.

Chemotherapy may be started during treatment with this medicine, or immediately after you stop taking it.

Do not take Tretiome 20mg Tablet if you are pregnant, planning pregnancy or breastfeeding as it can cause birth defects in babies.

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 1 month after you stop taking it.

Do not take any kinds of vitamin supplements without talking to your doctor first.

Your doctor may get regular blood tests done to monitor your blood lipid levels, liver function, blood cell count in your blood.

Do not use Tretiome 20mg Tablet if you are pregnant.

Inform your doctor if excessive skin dryness or skin sensitivity takes place.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tretiome 20mg Tablet is to be taken with food.


FAQs

Q. Can I undergo cosmetic procedures while taking Tretiome 20mg Tablet?

Your doctor will decide whether you can continue taking or stop taking Tretiome 20mg Tablet before cosmetic procedures. However, it is advised to not undergo hair removal or laser treatments while using Tretiome 20mg Tablet. Please inform your doctor about all the medicines you are taking before starting the treatment with this medicine. Also, consult the doctor before starting any cosmetic procedure.

Q. Is it safe to use Tretiome 20mg Tablet?

Yes, Tretiome 20mg Tablet is safe to use when taken as advised by your doctor. However, like all medicines, even this medicine has some side effects, but it is not necessary that anyone who is taking these medicines might get these side effects. Please talk to your doctor if you get any unpleasant effects while taking this medicine.

Q. How long am I supposed to use Tretiome 20mg Tablet?

Your doctor will decide the duration of your treatment depending on the severity of your disease and the results of your lab tests. Usually, the treatment with Tretiome 20mg Tablet takes around 4-5 months.

Q. I am taking Tretiome 20mg Tablet. What should I do if I am planning to become pregnant?

It is important to consult your doctor if you are planning to become pregnant while taking Tretiome 20mg Tablet. Ideally, pregnancy is not advised because this medicine can harm your baby. However, if you do get pregnant during the treatment with Tretiome 20mg Tablet, consult your doctor.