Manufacturer: Glenmark Pharmaceuticals Ltd
Salt Composition : Aztreonam(500mg)
Trezam 500mg Injection is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Rash, vomiting, nausea, and diarrhea may be seen as the most common side effects. Temporary pain, swelling, and redness at the injection site may also occur at the injection site. Consult your doctor if any of these side effects persist or if your condition does not improve despite treatment.
Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.
Trezam 500mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.
In inflamed meninges, penetration of aztreonam into CSF is more rapid than with uninflamed meninges. Diffusion through the placenta is poor, as is diffusion into breast milk. The main route of elimination of aztreonam is by the kidney, partly by active tubular excretion, but this can be inhibited by probenecid.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trezam
Rash
Injection site reactions (pain, swelling, redness)
Vomiting
Nausea
Diarrhea
This preparation is contraindicated in patients with known hypersensitivity to aztreonam or any other component in the formulation.
Trezam 500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol with Trezam 500mg Injection does not cause any harmful side effects.
Trezam 500mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Aztreonam for Injection is indicated for adjunctive therapy to surgery in the management of infections caused by susceptible organisms, including abscesses, infections complicating hollow viscus perforations, cutaneous infections, and infections of serous surfaces.
Drug-Drug Interaction: AZTREONAM may interact with warfarin (blood thinner), entecavir (antiviral), cholera vaccine (live), pemetrexed (used for non-small cell lung cancer), dicumarol (anticoagulant).
Drug-Food Interaction: Avoid taking alcohol while on this medication.
Drug-Disease Interaction: Inform your doctor if you have renal dysfunction, hemodialysis, or colitis (inflammation of the inner lining of the colon).
Drug-Drug Interactions Checker List:
WARFARIN
ENTECAVIR
CHOLERA VACCINE
PEMETREXED
DICUMAROL
Store below 30°C
Consult a doctor before taking any medicines.
Consult a doctor before taking any medicines.
You have been prescribed Trezam 500mg Injection for the treatment of bacterial infections.
It is given by an injection or drip into a vein or into a muscle in the buttock or thigh.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Trezam 500mg Injection safe to use in patients who are allergic to penicillins?
Trezam 500mg Injection can be safely used in patients who are allergic to penicillins. This medicine has shown no cross-reactivity when used in patients with penicillin allergy.
