Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Moclobemide(150mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Trima 150mg Tablet should be taken with food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. If you have missed any doses, take it as soon as you remember and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include nausea, vomiting, headache, fatigue, insomnia (difficulty sleeping), and dry mouth. Other side effects that may also be observed are constipation, restlessness, diarrhea, and agitation. However, these are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or worry you. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
Before taking this medicine, please tell your doctor if you suffer from any liver problems or diabetes. If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine.
Trima 150mg Tablet increases the levels of chemical messengers in the brain that helps in regulating the mood and treat depression.
In humans moclobemide is rapidly and almost completely absorbed and totally metabolised via the liver. Peak plasma levels occur 0.3 to 2 hours after oral administration.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trima
Nausea
Vomiting
Headache
Insomnia (difficulty in sleeping)
Dizziness
Dryness in mouth
Constipation
Restlessness
Diarrhea
Agitation
Confusional states.
Bipolar disorder (although it seems less likely than imipramine to cause a manic switch)
Phaeochromocytoma.
Trima 150mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Trima 150mg Tablet. Please consult your doctor.
Trima 150mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Moclobemide is a monoamine oxidase inhibitor used in the treatment of major depressive disorder and bipolar disorder. A reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder.
Drug-Drug Interactions: Inform the doctor if you are taking anti-depressants (fluoxetine, bupropion, paroxetine, clomipramine, St.John’s Wort), opioid partial agonist (buprenorphine), cough and cold medicines (dextromethorphan, ephedrine, pseudoephedrine, phenylpropanolamine), pain killer (pethidine, tramadol, morphine, codeine, fentanyl), anti-Parkinson agent (selegiline), anti-migraine agent (triptans), antibiotics (linezolid), or antacid (cimetidine).
Drug-Food Interactions: Avoid consuming large quantities of tyramine-containing foods such as mature cheese, yeast extract, or fermented soya bean products while on treatment with MOCLOBEMIDE.
Drug-Disease Interactions: Inform the doctor if you have manic disorder, severe mental health problems, an overactive thyroid, or serious liver disease.
Drug-Drug Interactions Checker List:
FLUOXETINE
BUPROPION
PAROXETINE
CLOMIPRAMINE
ST JOHN'S WORT
BUPRENORPHINE
DEXTROMETHORPHAN
EPHEDRINE
PSEUDOEPHEDRINE
PETHIDINE
TRAMADOL
MORPHINE
CODEINE
FENTANYL
SELEGILINE
LINEZOLID
CIMETIDINE
Do not chew, crush or break it. Trima 150mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Trima 150mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Trima 150mg Tablet should be taken with food, preferably at the same time every day.
Do not drive or do anything requiring concentration until you know how Trima 150mg Tablet affects you.
As a precaution, foods high in tyramine (e.g., aged cheeses, air-dried meats, soy sauce, tap/draft beers and red wines) should be avoided when taking Trima 150mg Tablet, as it may cause an unsafe rise in your blood pressure.
Inform your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trima 150mg Tablet is to be taken with food.
Avoid Trima 150mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Q. What is Trima 150mg Tablet and what it is used to treat?
Trima 150mg Tablet is an antidepressant that is used to treat depression and improves your mood.
Q. How long does it take for Trima 150mg Tablet to work?
Trima 150mg Tablet may take from a few days to several weeks to be really effective. The length of the treatment will depend on how quickly your symptoms improve. Most antidepressants take time to work so don't be discouraged if you don't feel better right away.
Q. What is the best time to take Trima 150mg Tablet?
Trima 150mg Tablet should be taken morning and evening at the end of your meal.
Q. Does Trima 150mg Tablet cause dry mouth?
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake, and sugarless candy may help.
