Trimine 25mg Tablet (10'S)

Manufacturer: Tripada Healthcare Pvt Ltd

Salt Composition : Imipramine(25mg)

₹8.50

Strip of 10 Tablet

(Inclusive of all taxes)



Basic Information

Mechanism Of Action

This medicine works by increasing the amount of a chemical substance in the brain which helps in maintaining the mental balance.


Pharmacokinets

Imipramine has a mean half life of 12 h. Its active metabolite, desipramine has a mean half life of 22.5 h 3. Imipramine has a mean clearance of 1 L/h/kg. Its active metabolite, desipramine has a mean clearance of 1.8 L/h/kg 3.


Side Effects

Major & minor side effects for Trimine 25 MG Tablet

Abdominal pain

Blurred vision

Decrease in frequency of urination

Dry mouth

Rapid weight gain

Yellow colored eyes or skin

Unusual tiredness and weakness

Increased sensitivity of the eyes to sunlight

Skin rash


Contra Indications

Imipramine is contraindicated in patients who have shown prior hypersensitivity to it and in acute porphyria, hepatic impairment and cardiovascular disease.


Pregnancy Related Information

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.


Breast Feeding Related Information

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.


Indications

Imipramine may be used to treat depression and nocturnal enuresis in children Label. Unlabeled indications include chronic and neuropathic pain (including diabetic neuropathy), panic disorder, attention-deficit/hyperactivity disorder (ADHD), and post-traumatic stress disorder (PTSD) 12,11,1,13,14,15,2.

Interactions

Drug-Drug Interactions: IMIPRAMINE may interact with anti-depressants (fluoxetine, fluvoxamine, duloxetine, escitalopram, sertraline), antipsychotics (aripiprazole, quetiapine), anti-convulsant (carbamazepine, phenytoin, phenobarbital, pregabalin, topiramate), benzodiazepine (diazepam, nitrazepam, oxazepam, alprazolam, clonazepam), pain killer (aspirin, tramadol, codeine, dihydrocodeine), anti-HIV (ritonavir), antacid (cimetidine, esomeprazole), blood thinner (warfarin), skeletal muscle relaxant (cyclobenzaprine), anti-anxiety (alprazolam) and hormone (levothyroxine).

Drug-Food Interactions: Do not take St. John’s wort (herbal supplement to treat depression) along with IMIPRAMINE.

Drug-Disease Interactions: Inform your doctor if you have epilepsy, low blood pressure, overactive thyroid, urination problems or enlarged prostate, glaucoma, diabetes, schizophrenia, mania, pheochromocytoma (tumour of the adrenal gland), heart, kidney or liver problems.

Drug-Drug Interactions Checker List:

FLUOXETINE

FLUVOXAMINE

DULOXETINE

ESCITALOPRAM

SERTRALINE

ARIPIPRAZOLE

QUETIAPINE

CARBAMAZEPINE

PHENYTOIN

PHENOBARBITAL

PREGABALIN

TOPIRAMATE

DIAZEPAM

NITRAZEPAM

OXAZEPAM

ALPRAZOLAM

CLONAZEPAM

ASPIRIN

TRAMADOL

CODEINE

DIHYDROCODEINE

RITONAVIR

CIMETIDINE

ESOMEPRAZOLE

WARFARIN

CYCLOBENZAPRINE

LEVOTHYROXINE

Storage Requirements

 Store below 30°C

Effects Of Missed Dosage

Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose then the missed dose should be skipped.


Effects Of Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.


Expert Advice

Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.


How To Use

Depression

Enuresis

FAQs

How long do the effects of this medicine last?

The amount of time for which this medicine remains active in the body is not clinically established.

Is it safe to consume alcohol while taking this medicine?

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.

Is this a habit forming medicine?

No habit forming tendencies were reported.