Manufacturer: Lupin Ltd
Salt Composition : Ciclesonide(400mcg), Formoterol(12mcg), Tiotropium(18mcg)
Bottle of 15 Transcaps
(Inclusive of all taxes)
Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.
The most common side effects are nausea, vomiting, dryness in the mouth, fungal infection of mouth, respiratory tract infection, bronchitis (inflammation of the airways), cough, sore throat, hoarseness of voice, and headache. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.
Trimium Transcaps is a combination of three medicines: Ciclesonide, formoterol and tiotropium. Ciclesonide is a corticosteroid. It acts by stopping the release of certain natural substances in body that are responsible for inflammation of the airways. Formoterol is a bronchodilator, while tiotropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.
Ciclesonide is a novel inhaled corticosteroid that possesses a unique pharmacokinetic and pharmacodynamic profile. Ciclesonide is inactive itself and converted to its pharmacologically active metabolite, desisobutyryl-ciclesonide, in the target organ, the lungs.Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.Formoterol, a long-acting beta 2-selective adrenoceptor agonist, produces dose-proportional bronchodilation in patients with obstructive airways disease with a reversible component. A significant effect occurs within minutes of inhalation of a therapeutic formoterol dose and persists for approximately 12 hours.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trimium
Dryness in mouth
Cough
Headache
Dry throat
Increased heart rate
Blurred vision
Glaucoma
Difficulty in urination
Urinary retention
Constipation
Nasopharyngitis (inflammation of the throat and nasal passages)
Upper respiratory tract infection
Sinus inflammation
Stomach discomfort
Fungal infection of oropharynx
Tremors
Palpitations
Voice change
Dizziness
Insomnia (difficulty in sleeping)
Paresthesia (tingling or pricking sensation)
Taste change
If you are suffering from any of the following diseases, you should not take Ciclesonide + Formoterol + Tiotropium unless your doctor advises you to do so -
Angioedema
Allergy
Infections
Herpes
Cataract
Glaucoma
Angioedema
Liver Disease
Kidney Disease
Asthma
Diabetes
Epilepsy
Heart Disease
Kidney Disease
Potassium Deficiency
Trimium Transcaps may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Trimium Transcaps.
Trimium Transcaps is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the baby for dry mouth, constipation, and urinary problems.
Use with caution
Below 9years: Contraindicated
Ciclesonide+Formoterol+Tiotropium is used in the treatment of chronic obstructive pulmonary disease.Ciclesonide is a corticosteroid. It acts by stopping the release of certain natural substances in body that are responsible for inflammation of the airways. Formoterol is a bronchodilator, while tiotropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.
CICLESONIDE+FORMOTEROL+TIOTROPIUM may interact with bronchodilators (albuterol), steroids (prednisone), diuretics (furosemide, amiloride), pain killers (aspirin), antibiotics (azithromycin), antidepressants (duloxetine), heart-related medicines (metoprolol), antifungals (itraconazole, voriconazole, posaconazole, ketoconazole), HIV/AIDS drugs (ritonavir), mono-amino oxidase inhibitors (phenelzine),
Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.
Store below 30°C
If you miss a dose of Trimium Transcaps, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Trimium Transcaps helps relieve symptoms of severe chronic obstructive pulmonary disease (COPD) such as cough, wheez and breathlessness.
This medicine is for inhalation only. The tablet should not be swallowed.
Take it at the same time each day.
It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
Very little amount of Trimium Transcaps may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Do not stop taking it suddenly even if you don’t currently have any symptoms as that may cause your breathing problems to come back.
Trancaps must not be swallowed. Check the label for directions before use. Place the capsule at the base of transhaler, not in the mouthpiece. Twist the mouthpiece completely until your hear a click and breathe in deeply through the mouthpiece. Hold your breath for up to 10 seconds. If some powder remains in the transhaler repeat the process.
