Manufacturer: Bharat Serums & Vaccines Ltd
Salt Composition : Urokinase(5000IU)
U Frag 5000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.
U Frag 5000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.
Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Urokinase acts to convert this plasminogen into plasmin and thereby to dissolve the thrombus. The plasmin thus generated within the fibrin clot is not affected by antiplasmins. According to Ambus et al., the plasmin thus activated by urokinase conjugates with anitplasmins and circulates in the blood.
Urokinase administered by intravenous infusion is rapidly cleared by the liver with an elimination half-life for biologic activity of 12.6 ± 6.2 minutes and a distribution volume of 11.5 L. Small fractions of the administered dose are excreted in bile and urine.
Allergic reaction
Nausea
Vomiting
Injection site bleeding
Decreased blood pressure
retinal disease with hemorrhage in diabetic patient. increased risk of bleeding due to clotting disorder. injury of the brain and spinal cord. puncture of artery that cannot have pressure exerted on it.
U Frag 5000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
It is not known whether it is safe to consume alcohol with U Frag 5000IU Injection. Please consult your doctor.
U Frag 5000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
For the lysis of acute massive pulmonary emboli, defined as obstruction of blood flow to a lobe or multiple segments. For the lysis of pulmonary emboli accompanied by unstable hemodynamics, i.e., failure to maintain blood pressure without supportive measures
Ask your doctor before taking aspirin or ibuprofen (Motrin, Advil) shortly after you have received urokinase. These medications can increase your risk of bleeding. Avoid activities that may increase your risk of bleeding or injury.
Your doctor or nurse will give you this medicine.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of U Frag 5000IU Injection, please consult your doctor.
Consult a doctor before taking any medicines
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Can the use of U Frag 5000IU Injection increase the risk of bleeding?
Yes, U Frag 5000IU Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking U Frag 5000IU Injection?
U Frag 5000IU Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
