U Tryp 100000IU (Injection)


U Tryp 100000IU Injection is used in the treatment of severe sepsis and inflammation of the pancreas (acute pancreatitis). It helps to reduce the chemicals involved in the inflammation of the pancreas.


U Tryp 100000IU Injection is generally administered by a doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.


The most common side effects are injection site reactions (pain, swelling, and redness) and increased liver enzymes. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.


U Tryp 100000IU Injection should not be used for patients who are hypersensitive and in breastfeeding women. Before taking this medicine, you should tell your doctor if you are pregnant or planning pregnancy. Your doctor may advise for regular liver function while you are taking this medicine. This medicine can not be used for replacing the traditional therapeutic methods such as transfusion, oxygen therapy and antibiotics for shocks.



Basic Information

Mechanism Of Action

Ulinastatin, a serine protease inhibitor, inhibits several pro-inflammatory proteases and decreases inflammatory cytokine levels and mortality in experimental sepsis. We studied the effect of ulinastatin on 28-day all-cause mortality in a double-blind trial in patients with severe sepsis in seven Indian hospitals

Pharmacokinets

Ulinastatin is an acid-resistant protease inhibitor found in human urine and released from the high-molecular-weight precursor I alpha T1. It inactivates many serine proteases, including trypsin, chymotrypsin, kallikrein, plasmin, granulocyte elastase, cathepsin, thrombin, and factors IXa, Xa, XIa, and XlIa.


Side Effects

Injection site reactions (pain, swelling, redness)

Increased liver enzymes


Contra Indications

This drug is not advised for women who are lactating or patients who are hyper sensitive to it. In patients with history of allergy Ulinastatin should be very cautiously administered. The side effects of this medicine may include rashes and infections at the site of injection.


Pregnancy Related Information

U Tryp 100000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with U Tryp 100000IU Injection. Please consult your doctor.


Breast Feeding Related Information

U Tryp 100000IU Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.


Indications

Ulinastatin also suppresses the activation of PMN cells, macrophages, and platelets. Derived from these properties, ulinastatin has been investigated as a potential clinical therapy for indications including shock and pancreatitis and approved in Japan and China with ongoing clinical trials around the globe.


Interactions

Ulinastatin is used in the treatment of severe sepsis and pancreatitis. Ulinastatin blocks the chemicals (digestive enzymes) which helps in digestion and also reduces the chemicals involved in inflammation of the pancreas

Typical Dosage

Your doctor or nurse will give you this medicine. 


Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

U Tryp 100000IU Injection is used to treat severe sepsis and pancreatitis.

Inform your doctor if you are pregnant or breastfeeding.

Let your doctor know if you have any history of allergy.


How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. Is U Tryp 100000IU Injection safe?

U Tryp 100000IU Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Q. What is U Tryp 100000IU Injection used for?

U Tryp 100000IU Injection is used for treating acute and chronic inflammation of pancreas (pancreatitis), septic conditions, trauma or inflammation post-surgery.