Manufacturer: Lupin Ltd
Salt Composition : Ursodeoxycholic Acid(300mg)
Ulyses 300 Tablet should be swallowed whole after a meal and with a glass of milk or water. The dose will depend on what you are being treated for and your body weight. Take it regularly to get maximum benefit and keep taking it for as long as prescribed (several months or longer). Keep taking it even if your symptoms disappear.
This medicine's most common side effects are abdominal pain, diarrhea, hair loss, itching, nausea, and rash. Not everyone gets these side effects. If you are worried about them, or they do not go away, let your doctor know.
Before taking this medicine, you should tell your doctor if you have an inflammation of the gallbladder or bile ducts, you get frequent cramp-like pain in your upper abdomen, you have been coughing up blood or you have gained weight rapidly. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor all other medicines you are taking. Women should discontinue hormonal birth control pills as they can increase the production of gallstones. During the treatment, you may need ultrasound scans, or frequent blood tests to check your liver function.
Ulyses 300 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.
Ursodeoxycholic acid is absorbed incompletely because of its low aqueous solubility. After absorption, it is conjugated with glycine or taurine and circulates with the endogenous bile acids. At usual doses (8-10 mg/kg/day), the pool of ursodeoxycholyl conjugates constitutes 30-60% of circulating bile acids.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ulyses
Abdominal pain
Diarrhea
Hair loss
Itching
Nausea
Rash
Hypersensitivity to Ulyses 300 Tablet is a contraindication. In addition, Ulyses 300 Tablet should not be used if you have the following conditions:
Antacids
Calcified and pigment gallstones
Chronic liver and peptic ulcer disease
Hypersensitivity
Inflammatory disease of colon and small intestine
Non functioning gall bladders
Pregnant
Radio opaque gallstones
Ulyses 300 Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Ulyses 300 Tablet may cause excessive drowsiness with alcohol.
Ulyses 300 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
Ursodeoxycholic acid is indicated in the treatment of primary biliary cirrhosis (PBC) and for the dissolution of radiolucent gallstones in patients with a functioning gall bladder. Hepatobiliary disorders associated with cystic fibrosis in children aged 6 to 18 years.
If you use other drugs or over the counter products at the same time, the effects of Ulyses 300 Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Ulyses 300 Tablet may interact with the following drugs and products:
Antacids
Cholestyramine
Colestipol
Oestrogens
Do not chew, crush or break it. Ulyses 300 Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Ulyses 300 Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Ulyses 300 Tablet should be taken after a meal with a glass of milk or water.
Eat a healthy diet, exercise regularly, and avoid alcohol intake.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Your doctor may monitor your liver function and bilirubin levels every month for the next 3 months after the start of therapy, and every 6 months thereafter.
Do not stop taking the medication without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ulyses 300 Tablet is to be taken with food.
Q. When should I take Ulyses 300 Tablet?
The suitable timing of taking this medicine might differ depending upon your condition. Your doctor might instruct you to take 2 to 3 doses per day and suggest to take the last dose at bedtime. Ulyses 300 Tablet should be taken with water milk and can be taken with food or after food. When prescribed for dissolving gallstones, it is usually suggested to be taken once daily at night. Ideally, it should be taken at a gap of 6 hours, for example at 8 am, 2 pm and 8 pm.
Q. Is Ulyses 300 Tablet safe?
Ulyses 300 Tablet is usually considered to be a safe and effective medicine. However, this medicine may have some common side effects, such as diarrhea. If diarrhea occurs, your doctor may reduce the dose and if it persists, your treatment may be discontinued. Additionally, using this medicine as a long-term therapy may also affect your liver enzyme levels. To keep a check on this, your doctor will keep monitoring your liver enzyme levels regularly. Despite these minor side effects, this medicine is supposed to be a good alternative to surgery in some patients with gallstones.
Q. How does Ulyses 300 Tablet help the liver?
Ulyses 300 Tablet acts on the liver and gets concentrated in the bile secreted from the liver. This, as a result, suppresses the synthesis and secretion of cholesterol by the liver, thereby decreasing the cholesterol levels in bile. This medicine also acts by stopping the intestines from absorbing the bile salts and cholesterol. So, the reduced cholesterol saturation in the bile from the liver leads to the gradual dissolving of cholesterol from gallstones, leading to a decrease in size and their eventual dissolution. It also reduces elevated liver enzyme levels by increasing the bile flow through the liver, hence protecting the liver cells.
Q. Does Ulyses 300 Tablet cause weight gain?
Yes, there is a chance of weight gain with Ulyses 300 Tablet, but it is not common. The use of Ulyses 300 Tablet can cause weight gain when prescribed in patients with liver disease associated with chronic stasis of bile in small bile ducts of the liver. In such condition, bile cannot flow from the liver to the small intestine. Again, the chance of weight gain varies from person to person depending upon the disease, so consult your doctor if you experience weight gain.
Q. What should I avoid while taking Ulyses 300 Tablet?
While taking Ulyses 300 Tablet, avoid taking an antacid preparation without consulting your doctor, as they decrease the effectiveness of Ulyses 300 Tablet. You should also avoid medicines like cholestyramine or colestipol as they affect the effectiveness of Ulyses 300 Tablet. So, ask your doctor about the time gap that should be maintained between Ulyses 300 Tablet and these medicines. Also, avoid taking oral contraceptives, estrogenic hormones and blood cholesterol-lowering agents such as clofibrate as they may increase the chances of developing gallstones and act opposite to the Ulyses 300 Tablet.
