Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Tenecteplase(50mg)
Velix 50mg Injection is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment.
The most common side effect of this medicine is bleeding. It may cause injection site bleeding, nosebleeds, blood in the stool, blood in the urine, or gastrointestinal bleeding. While on treatment with this medicine, you should be careful while shaving, cutting nails, or using sharp objects.
This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Velix 50mg Injection including if you’ve had a head injury or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.
Tenecteplase is a fibrin-specific tissue-plasminogen activator. It binds to fibrin rich clots and cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.
Tenecteplase has an initial half-life of 20 to 24 minutes with a terminal half-life of 90 to 130 minutes with a mean plasma clearance ranging from 99 to 119 mL/min. The initial volume of distribution approximates plasma volume and the major route of elimination is by hepatic metabolism.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metalyse
Injection site bleeding
Nosebleeds
Blood in stool
Blood in urine
Gastrointestinal bleeding
Tenecteplase is contraindicated in persons with aneurysm or arteriovenous malformation; known coagulopathy or bleeding diathesis; active internal bleeding; brain tumor; intracranial or intraspinal surgery or trauma (e.g., head trauma) within 2 months; or history of cerebrovascular accident (stroke).
Velix 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Velix 50mg Injection. Please consult your doctor.
Velix 50mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Tenecteplase is indicated for use in the reduction of mortality associated with acute myocardial infarction (AMI). Treatment should be initiated as soon as possible after the onset of AMI symptoms.
The risk or severity of bleeding can be increased when Alteplase is combined with Tenecteplase. The risk or severity of bleeding can be increased when Tenecteplase is combined with Altretamine. The therapeutic efficacy of Aminocaproic acid can be decreased when used in combination with Tenecteplase.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Velix 50mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Velix 50mg Injection is used to treat myocardial infarctions (heart attacks) as soon as possible (usually within 12 hours) after the onset of symptoms.
It is given as an injection into the vein under the supervision of a doctor.
It may increase your risk of bleeding. Inform your doctor immediately if you notice bleeding at the injection site, nose bleed, and blood in urine.
Continue with your diet and exercise along with previously prescribed medications for heart attack.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How is Velix 50mg Injection administered?
Velix 50mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Velix 50mg Injection.
Q. Is Velix 50mg Injection safe?
Velix 50mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. Can the use of Velix 50mg Injection increase the risk of bleeding?
Yes, Velix 50mg Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Q. What medicines should I avoid while taking Velix 50mg Injection?
Velix 50mg Injection can interact with several medicines. If you are already taking Velix 50mg Injection, do not take any other medicine without talking to your doctor.
Q. When will I feel better after taking Velix 50mg Injection?
Velix 50mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Velix 50mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.
