Manufacturer: Pfizer Ltd
Salt Composition : Voriconazole(50mg)
Vfend 50mg Tablet belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat a wide range of fungal infections. It kills fungi by destroying the fungal cell membrane.
Vfend 50mg Tablet should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole. It should be taken one hour before or one hour after a meal. The dosage and length of treatment will depend on the condition you are being treated for. Sometimes this will be in cycles of use and non-use. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse.
The most common side effects of this medicine include rash, vomiting, nausea, and headache. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat or face, swallowing or breathing problems, feeling dizzy or faint, and nausea. Get emergency help if this happens.
Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.
The mechanism of action of voriconazole, similar to that of all azole agents, is inhibition of cytochrome P450 (CYP 450)–dependent 14α-lanosterol demethylation, which is a vital step in cell membrane ergosterol synthesis by fungi
Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection
Abnormal liver function tests
Hallucination
Slow heart rate
Altered vision
Headache
Nausea
Rash
Vomiting
low amount of magnesium in the blood.
low amount of calcium in the blood.
low amount of potassium in the blood.
sudden blindness and pain upon moving the eye.
cardiomyopathy, a disease of the heart muscle.
torsades de pointes, a type of abnormal heart rhythm.
prolonged QT interval on EKG.
Vfend 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is unsafe to consume alcohol with Vfend 50mg Tablet.
Vfend 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
VFEND is indicated in adults and pediatric patients (2 years of age and older) for the treatment of candidemia in non-neutropenic patients and the following Candida infections: disseminated infections in skin and infections in abdomen, kidney, bladder wall, and wounds
hepatotoxicity.
QT prolongation.
renal dysfunction.
risk of pancreatitis.
Do not chew, crush or break it. Vfend 50mg Tablet is to be taken empty stomach.
Store below 30°C
Consult a doctor before taking any medicines
Your doctor has prescribed Vfend 50mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
It should be taken one hour before or one hour after a meal.
Do not take indigestion remedies (antacids) within two hours of taking Vfend 50mg Tablet.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Vfend 50mg Tablet is to be taken empty stomach.
Q. What is Vfend 50mg Tablet? What is it used for?
Vfend 50mg Tablet is a prescription medicine that belongs to a class of medicines known as antifungals. It is used to treat certain serious fungal infections in your blood and body such as aspergillosis, esophageal candidiasis, Scedosporium, Fusarium, and candidemia. Vfend 50mg Tablet effectively relieves these infections in adults and children aged 2 years and above.
Q. Is Vfend 50mg Tablet effective?
Vfend 50mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Vfend 50mg Tablet too early, the symptoms may return or worsen.
Q. What if I forget to take a dose of Vfend 50mg Tablet?
If you have missed a dose of Vfend 50mg Tablet, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. What should I know before taking Vfend 50mg Tablet?
Before taking Vfend 50mg Tablet, you should tell your doctor if you are allergic to Vfend 50mg Tablet or any of its ingredients to avoid any allergic reactions. Let your doctor know if you have any problems with your heart, liver or kidneys and if you are suffering from diabetes as Vfend 50mg Tablet contains sugar. Inform your doctor about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby
