Manufacturer: Novo Nordisk India Pvt Ltd
Salt Composition : Liraglutide(6mg/ml)
Victoza Solution for Injection belongs to the GLP-1 (glucagon-like peptide) group of diabetes medicines. It works by helping your body produce insulin and by reducing appetite. It also helps to reduce weight in some people. This medicine should be stored in a refrigerator until you need it but do not freeze it.
It is normally injected under the skin once daily. The dose will depend on your condition and what other diabetes medicines you are taking. You can use it at any time of the day with or without food but try to use it at the same time each day to get the most benefit. Your doctor or nurse will show you how and where to inject the medicine. Follow the instructions carefully.
Do not stop taking this medicine without talking to your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications. Remember that it is only part of a treatment program that should also include a healthy diet and regular exercise as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.
The most common side effects of this medicine include nausea, diarrhea, vomiting, decreased appetite, indigestion, and constipation. It can also lead to low blood sugar levels (hypoglycemia) especially if you are also taking other medicines like insulin or sulphonylureas for treatment of diabetes. To prevent this, it is important to have regular meals and always carry a fast-acting source of glucose such as sugary candy or glucose candy with you.
Before using it, let your doctor know if you have any pancreas or stomach problems or severe dehydration (loss of body water), or diabetic ketoacidosis (a complication of diabetes characterized by too much acid and ketones in your blood). This medicine may not be suitable. Pregnant or breastfeeding women should also consult their doctor before using this medicine. If you experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar, do not drive, use machinery or do any activity that requires alertness or clear vision until you are sure you can do them safely.
Victoza Solution for Injection is an anti-diabetic medication. It works by increasing the release of insulin from pancreas, decreases hormones that raise blood sugar levels, slows down digestion, and reduces appetite.
33 Liraglutide was shown to be slowly absorbed, with a Tmax of 11–13 hours and half-life of 12–14 hours. In patients with type 2 diabetes, pharmacokinetic properties of subcutaneous liraglutide 6 µg/kg once/day were evaluated using 24-hour plasma profiles.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Victoza
Constipation
Decreased appetite
Diarrhea
Nausea
Vomiting
Abdominal pain
Dyspepsia
Flatulence
Nasopharyngitis (inflammation of the throat and nasal passages)
A boxed warning in the product labeling states that liraglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or in those with multiple endocrine neoplasia syndrome type-2 (MEN-2).
Victoza Solution for Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is unsafe to consume alcohol with Victoza Solution for Injection.
Victoza Solution for Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
as an adjunct to diet and exercise to improve glycemic control in adults and pediatric patients aged 10 years and older with type 2 diabetes mellitus, • to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in .
Drug-Drug Interaction: LIRAGLUTIDE may interact with other anti-diabetic medicines (insulin glargine, insulin degludec), hormones (levothyroxine), corticosteroids (prednisone), psychiatric medicines (olanzapine), antibiotics (ciprofloxacin), high blood pressure medicines (propranolol, metoprolol), and glaucoma eye drops (timolol).
Drug-Food Interaction: Limit alcohol intake since it affects blood sugar levels. Avoid fatty foods and include healthy carbohydrates in your diet.
Drug-Disease Interaction: Tell your doctor before taking LIRAGLUTIDE if you have a medical history of allergic reactions to medicines, heart, kidney or liver diseases, pancreatitis (inflammation of the pancreas), stomach disorders like gastroparesis (delayed gastric emptying), high cholesterol levels, gallbladder problems, and depression. LIRAGLUTIDE is contraindicated in patients with multiple endocrine neoplasia type 2 (tumours in thyroid and parathyroid glands) and personal or family history of thyroid cancer.
Drug-Drug Interactions Checker List:
INSULIN GLARGINE
INSULIN DEGLUDEC
LEVOTHYROXINE
PREDNISONE
OLANZAPINE
CIPROFLOXACIN
PROPRANOLOL
METOPROLOL
TIMOLOL
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Victoza Solution for Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Victoza Solution for Injection should be injected under the skin of your abdomen or thigh at the same time everyday. Do not administer intravenously or intramuscularly.
Store the pen in the refrigerator. When refrigeration is not possible, you can also keep your pen at room temperature (less than 30°C) for up to 2 weeks. Do not freeze it.
Victoza Solution for Injection may cause nausea. To avoid it, eat smaller meals, limit fatty food intake and stop eating when you feel full.
Notify your doctor immediately if you have severe and/or persistent upper abdominal pain and vomiting.
Your doctor or nurse will guide you how to use this medicine.
Q. Is it better to take Victoza Solution for Injection in the morning or at night?
It is advised to take Victoza Solution for Injection once daily at any time of the day, but preferably at the same time each day. Victoza Solution for Injection comes as a solution (liquid) in a prefilled dosing pen to inject subcutaneously (under the skin) in your stomach, thigh, or upper arm.
Q. What things need to be checked before injecting Victoza Solution for Injection? How should I inject Victoza Solution for Injection?
Always look at the Victoza Solution for Injection solution before injecting it. It should be clear, colorless, and free of particles. Do not use Victoza Solution for Injection if it is colored, cloudy, thickened, or contains solid particles, or expired. You should inject it below the skin (subcutaneously) and not in vein or muscle. It is important to learn the technique before injecting it yourself.
Q. What are the other uses of Victoza Solution for Injection?
Victoza Solution for Injection is used along with diet and exercise program to control blood sugar levels in patients with type 2 diabetes mellitus. It is also used to prevent heart attack, stroke or death in adults with type 2 diabetes mellitus, and heart and blood vessel disease.
Q. Can I use other anti-diabetic medicines along with Victoza Solution for Injection?
Yes, you can use other anti-diabetic medicines but the dose needs to be adjusted. Do not mix other insulins with Victoza Solution for Injection. It is important to know that, other medicines which have similar mechanism of action should not be used like exenatide or lixisenatide with Victoza Solution for Injection.
