Vinobulin 300mcg Injection (2ml)


Vinobulin 300mcg Injection is given for Rh prophylaxis in pregnancy-related complications. It is also approved for Incompatible transfusions in Rh-negative individuals transfused with blood components containing Rh-positive red blood cells (RBCs). It may also be used for immune thrombocytopenic purpura, a condition wherein the number of circulating platelets decrease leading to easy bruising.


Your doctor or nurse will give you this injection. Kindly do not self administer. The injection is given into a muscle; normally it is given in the upper arm. You will be offered an anti-D injection routinely at 28 weeks of pregnancy and within 72 hours of birth if your baby is Rh D positive.


This medicine is genrally safe with no common side effects. However, if you get any symptoms on receiving the injection, you should tell your doctor. There may be ways of preventing or reducing these symptoms.


Before using it, you should tell your doctor if you have any problems with blood clotting and if you have recently had, or plan to have, a vaccination.


Basic Information

Mechanism Of Action

Anti-Rh D immunoglobulin belongs to class of drugs called immunoglobulin. It removes or nullifies any fetal rhesus-D positive red blood cells that enter the rhesus-D negative maternal blood stream during childbirth, abortion, or any accident or intervention during pregnancy which might lead to bleeding across the placenta.


Pharmacokinets

The pharmacokinetics of the redistribution of anti-D between injection site, intravascular and extravascular spaces following either intramuscular or intravenous administration is included, also the reaction of anti-D with D-positive red cells in the intravascular space and subsequent circulatory clearance of antibody- ...

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Vinobulin

No common side effects seen

Contra Indications

A hemolytic reaction may result if given to Rh-positive patients; RhIG should be avoided in these individuals.

Patients with a history of severe hypersensitivity or anaphylaxis to any human immune globulin product.

Pregnancy Related Information

Vinobulin 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Vinobulin 300mcg Injection. Please consult your doctor.


Breast Feeding Related Information

Vinobulin 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

Immune thrombocytopenic purpura (ITP) Rh(D)-positive, non-splenectomized. Chronic ITP in children and adults. Acute ITP in children. ...

Rh isoimmunization suppression. Rh(D)-negative, non-sensitized patient with Rh-incompatible fetus. Prophylaxis in the following clinical situations:


Interactions

Drug-Drug Interactions: ANTI RH D IMMUNOGLOBULIN may interact with the vaccine taken against measles, mumps, and rubella (MMR) and the vaccine taken against chickenpox (varicella), making them less effective. So, these vaccines should be delayed for at least three months after taking ANTI RH D IMMUNOGLOBULIN.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: ANTI RH D IMMUNOGLOBULIN should be used with caution in people with clotting disorders, thrombocytopenia (reduced number of platelets) and with immunoglobulin A (IgA) deficiency (IgA is a type of antibody that protects against infections).

Drug-Drug Interactions Checker List:

VARICELLA (LIVE ATTENUATED)

MMR VACCINE

Storage Requirements

Store in a refrigerator (2 - 8°C). Do not freeze.


Effects Of Missed Dosage

If you miss a dose of Vinobulin 300mcg Injection, please consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Consult a doctor before taking any medicines.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

FAQs

Q. What does anti-D antibody mean?

If you're RhD negative, your blood will be checked for the antibodies (known as anti-D antibodies) that destroy RhD positive red blood cells. If anti-D antibodies are detected in your blood during pregnancy, there's a risk that your unborn baby may get affected by rhesus disease.

Q. Why do I need Vinobulin 300mcg Injection?

Vinobulin 300mcg Injection is needed to prevent a disease called Rhesus disease. This can help to avoid a process known as sensitisation in women. This is a condition when a woman with RhD negative blood is exposed to RhD positive blood and develops an immune response to it.

Q. How is Vinobulin 300mcg Injection administered?

Vinobulin 300mcg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. Vinobulin 300mcg Injection is given into a muscle, normally in the upper arm. Follow your doctor’s instructions carefully to get maximum benefit from Vinobulin 300mcg Injection.

Q. When is Vinobulin 300mcg Injection given?

Vinobulin 300mcg Injection will be given as an injection at 28 weeks of pregnancy and within 72 hours of birth, if your baby is Rh D positive. Consult your doctor before getting Vinobulin 300mcg Injection.