Vorizol 200mg Injection

Manufacturer: Natco Pharma Ltd

Salt Composition : Voriconazole(200mg)


Vorizol Injection belongs to a group of medicines called antifungals. It works by stopping the growth of fungus and is used to treat a wide range of fungal infections. It kills fungi by destroying the fungal cell membrane.


Vorizol Injection is administered under the supervision of a doctor or a nurse. Do not self-administered the injection. To get the most benefit, get the injection at evenly spaced times and continue taking it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.


The most common side effects of this medicine include rash, vomiting, nausea, and headache. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction. Signs of this include rash, swelling of the lips, throat, or face, swallowing or breathing problems, feeling dizzy or faint, and nausea. Get emergency help if this happens.


Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood. The medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.



Basic Information

Mechanism Of Action

The mechanism of action of voriconazole, similar to that of all azole agents, is inhibition of cytochrome P450 (CYP 450)–dependent 14α-lanosterol demethylation, which is a vital step in cell membrane ergosterol synthesis by fungi

Pharmacokinets

Voriconazole is in a class of antifungal medications called triazoles. It works by slowing the growth of the fungi that cause infection

Side Effects

Rash

Headache

Vomiting

Nausea

Altered vision

Slow heart rate

Hallucination

Abnormal liver function tests

Contra Indications

low amount of magnesium in the blood.

low amount of calcium in the blood.

low amount of potassium in the blood.

sudden blindness and pain upon moving the eye.

cardiomyopathy, a disease of the heart muscle.

torsades de pointes, a type of abnormal heart rhythm.

prolonged QT interval on EKG.


Pregnancy Related Information

Vorizol Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Vorizol Injection.


Breast Feeding Related Information

Vorizol Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

VFEND is indicated in adults and pediatric patients (2 years of age and older) for the treatment of candidemia in non-neutropenic patients and the following Candida infections: disseminated infections in skin and infections in abdomen, kidney, bladder wall, and wounds

Interactions

hepatotoxicity.

QT prolongation.

renal dysfunction.

risk of pancreatitis.


Typical Dosage

 Kindly do not self administer.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Vorizol Injection, consult your doctor.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Your doctor has prescribed Vorizol Injection to cure your infection and improve symptoms.

Do not skip any doses and finish the full course of treatment even if you feel better.

It is given as an injection under the supervision of a healthcare professional.

Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

How To Use

Your doctor or nurse will give you this medicine. Kindly do not self administer.


FAQs

Q. What is Vorizol Injection? What is it used for?

Vorizol Injection is a prescription medicine that belongs to a class of medicines known as antifungals. It is used to treat certain serious fungal infections in your blood and body such as aspergillosis, esophageal candidiasis, Scedosporium, Fusarium, and candidemia. Vorizol Injection effectively relieves these infections in adults and children aged 2 years and above.

Q. Is Vorizol Injection effective?

Vorizol Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Vorizol Injection too early, the symptoms may return or worsen.

Q. What should I know before taking Vorizol Injection?

Before taking Vorizol Injection, you should tell your doctor if you are allergic to Vorizol Injection or any of its ingredients to avoid any allergic reactions. Let your doctor know if you have any problems with your heart, liver or kidneys and if you are suffering from diabetes as Vorizol Injection contains sugar. Inform your doctor about all the other medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding to prevent any harmful effects on the baby.

Q. What should I avoid while taking Vorizol Injection?

Driving or anything requiring concentration must be avoided while taking Vorizol Injection. This is because Vorizol Injection may cause changes in your vision such as blurring or sensitivity to light. Moreover, Vorizol Injection may make you sensitive to sunlight and increases the chances of getting a sunburn. If you get a sunburn, please contact your doctor immediately.