Manufacturer: Bayer Pharmaceuticals Pvt Ltd
Salt Composition : Rivaroxaban(20mg)
Xarelto 20mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It should be taken with food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
The most common side effect of Xarelto 20mg Tablet is bleeding more easily than normal, for example, having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
Rivaroxaban competitively inhibits Factor Xa and is more than 10,000-fold more selective for Factor Xa than other related serine proteases, and it does not require cofactors (such as antithrombin) to exert its anticoagulant effect.
Rivaroxaban produces a pharmacodynamic effect that is closely correlated with its plasma concentration. The pharmacokinetic and pharmacodynamic relationship for inhibition of Factor Xa activity can be described by an E max model, and prothrombin time prolongation by a linear model.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xarelto
Bleeding
Allery: Severe hypersensitivity to rivaroxaban (or any component of the formulation) can occur.
Hematologic: Active pathological bleeding is a contraindication for rivaroxaban use.
Xarelto 20mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Xarelto 20mg Tablet. Please consult your doctor.
Xarelto 20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Rivaroxaban is used to treat and manage venous thromboembolism as a postoperative thromboprophylaxis for patients undergoing orthopedic surgery to prevent stroke in patients with non-valvular atrial fibrillation and recently has received approval as an add-on drug for secondary prevention of acute coronary syndrome
Some products that may interact with this drug are: mifepristone, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, "blood thinners" such as warfarin, enoxaparin), certain antidepressants (including SSRIs such as fluoxetine, SNRIs such as desvenlafaxine/venlafaxine).
Do not chew, crush or break it. Xarelto 20mg Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Xarelto 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
For best results, take Xarelto 20mg Tablet at the same time every day. It is better to take at night with meals.
It interacts less with food or other medicines. Hence, frequent dose changes are not required.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
It may cause dizziness. Avoid driving or activity requiring mental focus until you know how it affects you.
If you are going to have a surgery or dental treatment, you may be asked to stop taking Xarelto 20mg Tablet temporarily.
Notify your doctor if you have any kidney problem.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking medication without talking to your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xarelto 20mg Tablet is to be taken with food.
Q. What are the side effects of Xarelto 20mg Tablet?
The most common side effects of Xarelto 20mg Tablet include long or excessive bleeding, breathlessness (which may be a sign of bleeding), exceptional weakness, tiredness, paleness, dizziness, headache, and unexplained swelling. Other side effects can be severe skin and allergic reactions, bruising, coughing up blood, bleeding from the skin or under the skin, and swelling and pain in the limbs. Using Xarelto 20mg Tablet may increase the bilirubin and decrease the number of platelets. Some people may experience fainting episodes, faster heartbeat, and dry mouth. In case you notice any side effects, immediately contact your doctor.
Q. Is Xarelto 20mg Tablet a blood thinner?
Yes, Xarelto 20mg Tablet is a blood thinner. It is a medication that prevents the blood from clotting within the blood vessels. It also prevents the blood clots from recurring in the blood vessels. It may be prescribed to treat blood clots in the veins of the legs and in the blood vessels of the lungs.
Q. Is Xarelto 20mg Tablet dangerous?
Xarelto 20mg Tablet has numerous beneficial effects, but it has a tendency to make you bleed more than normal come even with minor injuries as it reduces your blood’s clotting ability. Sometimes Xarelto 20mg Tablet may cause serious bleeding which may be dangerous and may need urgent medical attention. This risk may be higher in people taking Xarelto 20mg Tablet along with other blood thinning medications. Contact your doctor if you notice even minor bleeding.
Q. What foods should you avoid if you are on blood thinners?
Avoid taking grapefruit and grapefruit juice while taking Xarelto 20mg Tablet. The reason being, grapefruit contains compounds that slow down the metabolism of Xarelto 20mg Tablet and increase the activity leading to bleeding. On the other hand, if you are taking some other blood thinner like warfarin, you should avoid taking any food that increases the activity of vitamin K or increases the clotting of blood. Such food items may include spinach, brussels, sprouts, mustard greens, broccoli, asparagus and green tea. However, the use of these food items is not restricted with Xarelto 20mg Tablet.
