Manufacturer: Emcure Pharmaceuticals Ltd
Salt Composition : Filgrastim(300mcg)
Xgrast 300mcg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. You might be asked to get regular tests done to check the number of blood cells in your blood and your bone density level while you are taking this medicine.
The most common side effects of this medicine include bone pain, weakness, headache, and rash. Other than this, pain or redness at the site of injection is common. But, inform your doctor if you notice a lump, swelling, or bruising that does not go away. It might not prevent you from all kinds of infection, hence inform your doctor if you notice fever, chills, rash, sore throat, and swelling around the face or neck.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood. It has a number of therapeutic uses, including the management and prevention of infections and febrile neutropenia in patients receiving myelosuppressive chemotherapy or radiation therapy
Filgrastim increases the peripheral blood neutrophil count and causes a minor increase in monocytes. Filgrastim also mobilizes CD34+ stem cells; CD34+ stem cells in the peripheral blood serve as an indirect indicator of the marrow-repopulating ability of peripheral blood progenitor cells
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Xgrast
Bone pain
Weakness
Headache
Rash
Nausea
Increased lactate dehydrogenase level in blood
Vomiting
Increased uric acid level in blood
Oropharyngeal pain
Hair loss
Fatigue
Diarrhea
Constipation
Decreased appetite
Cough
Breathing problems
Injection site reactions (pain, swelling, redness)
Filgrastim is contraindicated for use in patients with a history of serious allergic reactions to granulocyte colony-stimulating factors such as filgrastim or pegfilgrastim or any other component of the product
Xgrast 300mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Xgrast 300mcg Injection. Please consult your doctor.
Xgrast 300mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Filgrastim is indicated for chronic administration to reduce the incidence and duration of sequelae of neutropenia (e.g.‚ fever‚ infections‚ oropharyngeal ulcers) in symptomatic patients with congenital neutropenia‚ cyclic neutropenia‚ or idiopathic neutropenia.
Filgrastim has no noted severe interactions with any other drugs. Filgrastim has no noted serious interactions with any other drugs. Filgrastim has no noted moderate interactions with any other drugs. Filgrastim has no noted minor interactions with any other drugs
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Xgrast 300mcg Injection, please consult your doctor.
Consult a doctor before taking any medicines
Xgrast 300mcg Injection reduces the risk of infection in people treated with chemotherapy.
It is usually given as a daily injection into the tissue just under the skin or into the vein.
You will normally receive your first dose at least 24 hours after your chemotherapy or bone marrow transplant.
Store it in the refrigerator, protect it from light, and don't shake it.
For a more comfortable injection, leave the syringe at room temperature for 30 minutes before using it.
Pain or redness in the area of injection is common. Let your doctor know if you notice a lump, swelling, or bruising that doesn't go away.
Use caution while driving or doing anything that requires concentration as Xgrast 300mcg Injection may cause dizziness.
Your doctor may get regular tests done to monitor the number of blood cells in your blood, and your bone density level while you are receiving treatment with this medicine.
Stop taking Xgrast 300mcg Injection and inform your doctor if you have a fever, shortness of breath, fast rate of breathing or trouble breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. Is Xgrast 300mcg Injection safe?
Xgrast 300mcg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. How does Xgrast 300mcg Injection work?
Xgrast 300mcg Injection works by stimulating the bone marrow (organ in the body where blood cells are produced) to increase the production of specific types of blood cells called neutrophils that help fight infections.
Q. What are the uses of Xgrast 300mcg Injection?
Xgrast 300mcg Injection is used during cancer treatment (chemotherapy), bone marrow transplantation, severe chronic neutropenia (low number of a type of white blood cells called neutrophils), neutropenia in patients with HIV infection, and before stem cell donation.
Q. Does Xgrast 300mcg Injection cause cancer?
No, Xgrast 300mcg Injection does not cause cancer.
Q. Why does Xgrast 300mcg Injection cause bone pain?
The exact cause in unknown, but bone pain is a common side-effect of Xgrast 300mcg Injection.
