Manufacturer: Janssen Pharmaceuticals
Salt Composition : Trabectedin(1mg)
Yondelis Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include headache, fatigue, vomiting, weakness and increased liver enzyme. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and kidney. Generally, avoid alcohol consumption while on treatment.
Yondelis Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor’s instructions carefully and let your doctor know if any of the side effects bother you.
YONDELIS is an alkylating drug that binds guanine residues in the minor groove of DNA, forming adducts and resulting in a bending of the DNA helix towards the major groove.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Yondelis
Headache
Fatigue
Vomiting
Weakness
Nausea
Increased liver enzymes
Low blood platelets
Increased creatine phosphokinase (CPK) level in blood
Decreased white blood cell count (neutrophils)
Decreased appetite
Constipation
If you are suffering from any of the following diseases, you should not take Trabectedin unless your doctor advises you to do so -
Heart Disease
Liver Disease
Herpes
Infertility
Information regarding the use of Yondelis Injection during pregnancy is not available. Please consult your doctor.
It is unsafe to consume alcohol with Yondelis Injection.
Information regarding the use of Yondelis Injection during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Trabectedin belongs to class of drugs called alkylating agents. It works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying.
The metabolism of Trabectedin can be increased when combined with Carbamazepine. The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Carbimazole is combined with Trabectedin. The risk or severity of adverse effects can be increased when Carboplatin is combined with Trabectedin.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Yondelis Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Yondelis Injection is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Inform your doctor if you notice yellowing of eyes or skin, dark urine, muscle pain and skin rash.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
Kindly do not self administer.
