Manufacturer: Jagsonpal Pharmaceuticals Ltd
Salt Composition : Ulipristal acetate(5mg)
Yuliprist Tablet is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus). It is used for intermittent treatment and pre-operative treatment of uterine fibroid in women of reproductive age.
Yuliprist Tablet reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a glass of water. You should take this medicine for as long as it is prescribed for you. It is important to note that this medicine makes birth control less effective so use proper contraceptive methods to avoid pregnancy.
The most common side effects of this medicine include amenorrhea (absence of menstrual period) and headache. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. This medicine might stop your period for some time, but it happens again when you stop taking the medicine. Usually, your periods get stops within 10 days of taking the medicine, consult with your doctor if you still experience heavy bleeding.
Before taking this medicine, let your doctor know if you have ever had liver problems or severe asthma. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for liver functioning.
Ulipristal acetate exerts its pharmacological activity by binding to the body's progesterone receptors to produce an anti-progesterone contraceptive effect on the ovary (by suppressing or delaying ovulation) and on the endometrium (by decreasing endometrial thickness).
Ulipristal acetate is a derivative of 19-norprogesterone. The half-life after oral intake is 32 h; it binds to plasma proteins for 97–99%, and it is metabolized by the citochrome P450
Absence of menstrual periods
Headache
Endometrial hyperplasia
This medication must not be used during pregnancy. If you become pregnant or think you may be pregnant, tell your doctor right away. This drug passes into breast milk. Because of the possible risk to the infant, breast-feeding while using this drug is not recommended.
Yuliprist Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Yuliprist Tablet. Please consult your doctor.
Yuliprist Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Ulipristal acetate is indicated for intermittent treatment of moderate to severe symptoms of uterine fibroids in adult women who have not reached menopause when uterine fibroid embolisation and/or surgical treatment options are not suitable or have failed
Apalutamide. Apalutamide is predicted to decrease the efficacy of Ulipristal. ...
Aprepitant. Aprepitant decreases the efficacy of Ulipristal. ...
Atazanavir. ...
Bosentan. ...
Carbamazepine. ...
Clarithromycin. ...
Cobicistat. ...
Combined hormonal contraceptives.
Swallow it as a whole. Do not chew, crush or break it. Yuliprist Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Yuliprist Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Yuliprist Tablet is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking Yuliprist Tablet.
Your periods will usually start again within four weeks of stopping Yuliprist Tablet.
Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Yuliprist Tablet as it may make hormonal contraceptives (such as pills) less effective.
Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Yuliprist Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. How does Yuliprist Tablet work for fibroids?
Yuliprist Tablet acts by blocking the receptors of progesterone, which decreases the levels of progesterone and therefore it is helpful in decreasing the size of fibroids. Fibroids are non-cancerous development around the uterus. When given at a certain prescribed dose, Yuliprist Tablet inhibits ovulation leading to stopping of periods. As a result, it may benefit women who have heavy bleeding due to fibroids.
Q. Does Yuliprist Tablet stop periods?
No, taking a single tablet of Yuliprist Tablet does not stop periods, but it may delay or prepone your periods. In some cases you may have bleeding in between your periods. Consult your doctor if this happens.
Q. Can ulipristal be used as regular birth control medicine?
No, Yuliprist Tablet cannot be used as a regular contraceptive. It is meant for occasional use as an emergency contraceptive. It is important to know that the safety and effectiveness of Yuliprist Tablet have not been established for repeated use in one menstrual cycle. Hence, its repeated use is not recommended.
Q. How and when should Yuliprist Tablet be taken?
Yuliprist Tablet should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.
