Manufacturer: Wockhardt Ltd
Salt Composition : Chlorpheniramine Maleate(1mg/5ml), Paracetamol(125mg/5ml), Phenylephrine(5mg/5ml), Sodium Citrate(60mg/5ml), Menthol(1mg/5ml)
Bottle of 60ml Syrup
(Inclusive of all taxes)
This medication may be taken with or without food preferably one hour before you travel. Take it in a dose and duration as advised by the doctor. But, before taking it, inform doctor if you are suffering from depression and taking its medicines.Dizziness may occur as its side effect, so do not drive or do anything that requires mental focus. You should avoid drinking alcohol while taking this medicine, as it may cause excessive sleepiness.
Zedex Cough Syrup is a combination medicine used in the treatment of dry cough. It works by reducing the activity of cough center in the brain. It relieves allergic symptoms like runny nose, watery eyes, sneezing, throat irritation.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.Oral phenylephrine is extensively metabolized by monoamine oxidase, an enzyme that is present on the mitochondrial membrane of cells throughout the body. Compared to intravenous pseudoephedrine, phenylephrine has a reduced and variable bioavailability; only up to 38%.Citrate is a weak base and so reacts with hydrochloric acid in the stomach to raise the pH. It it further metabolized to bicarbonate which then acts as a systemic alkalizing agent, raising the pH of the blood and urine 8. It also acts as a diuretic and increases the urinary excretion of calcium.Menthol is a selective activator of transient receptor potential melastatin-8 (TRPM8) channels and is also a vasoactive compound. As a topical agent, it acts as a counter-irritant by imparting a cooling effect and by initially stimulating nociceptors and then desensitizing them.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zedex Cold
Dryness in mouth
Sleepiness
Drowsiness
Loss of appetite
Nausea
Insomnia (difficulty in sleeping)
Constipation
Vomiting
Headache
High blood pressure
Arrhythmia (irregular heartbeats)
Blurred vision
Breathlessness
Itching
Restlessness
Reflex bradycardia
Excitation
Epigastric pain
Neck pain
Tremors
Hypertensive crisis
Eye pain
Stinging in the eyes
Photophobia
Conjunctival sensitivity
Preterm and low birth weight infants
Fainting
Myocardial infarction
Subarachnoid hemorrhage
If you are suffering from any of the following diseases, you should not take Zedex Cold unless your doctor advises you to do so -
Drug Allergy
Kidney Disease
Shock
Liver Disease
Drug Allergies
Alcoholism
Phenylketonuria (PKU)
Neutropenia
Angina
Heart Disease
Coronary Artery Disease (CAD)
Hyperthyroidism
Diabetes
Glaucoma
Thyroid
Zedex Cold Syrup is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is unsafe to consume alcohol with Zedex Cold Syrup.
Information regarding the use of Zedex Cold Syrup during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Chlorpheniramine Maleate + Paracetamol + Phenylephrine + Sodium Citrate + Menthol is relieve cold symptoms. Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that cause pain and fever. Phenylephrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose. Sodium Citrate is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Menthol is an organic compound which produces a sensation of coolness and relieves minor throat irritation.
If you take other medicines or over the counter products at the same time, the effect of Zedex Cold Syrup may change. This can increase the risk of side effects or prevent the medicine from working. Tell your doctor about all the medications, vitamins, and herbal supplements you are using so your doctor can help prevent and manage drug reactions. Zedex Cold Syrup may interact with the following drugs and products:
Alcohol
Decongestants
Digoxin
High blood pressure medicines
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Leflunomide
Prilocaine
Teriflunomide
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Zedex Cold Syrup may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Zedex Cold Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Chlorpheniramine Maleate
Avoid driving or operating dangerous machinery as it may decrease alertness.
Avoid consuming alcohol when taking the Chlorpheniramine Maleate, as it may cause excessive sleepiness or drowsiness.
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylephrine
Oral phenylephrine should be taken with food
Phenylephrine can make you restless, so don't take it too close to bedtime
Do not use this medicine without doctor's advice if you are pregnant or breast feeding
Smoking may worsen the effect; therefore use of tobacco should be avoided.
Sodium Citrate
Sodium Citrate helps in thinning and removal of the mucus (slimy and sticky substance) from the airways, thereby treats various respiratory conditions.
Measure the syrup with a special dose-measuring spoon or cup, not a regular table spoon.
Inform your doctor if you have suffered or are currently suffering from any stomach, liver or kidney problem.
Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Zedex Cold Syrup may be taken with or without food, but it is better to take it at a fixed time.
Chlorpheniramine Maleate
Q. Does chlorpheniramine or chlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?
Chlorpheniramine causing these side effects is common or rare. Always consult your doctor, if you experience any of these side effects
Q. Is chlorpheniramine like Benadryl?
No, chlorpheniramine is different from Benadryl
Q. Is chlorpheniramine prescription?
Yes, it is available with doctor’s prescription only
Q. Can I take chlorpheniramine or chlorpheniramine maleate with Panadol/ cetirizine /Zyrtec/ Allegra/ warfarin/ diphenhydramine/ ibuprofen/Claritin/guaifenesin/Benadryl?
Yes, but taking other medicines may alter the effects of chlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does chlorpheniramine contain aspirin?
No, it does not contain aspirin in it. Chlorpheniramine is a different drug than aspirin.
Paracetamol
Q. What if I vomit after taking Paracetamol?
If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Q. When will I feel better after taking the Paracetamol?
Usually, you will start feeling better after about half an hour of taking a Paracetamol.
Q. How often can I take the Paracetamol?
You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.
Q. Does Paracetamol make babies sleepy?
No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Q. Is Paracetamol safe for children?
Paracetamol is considered safe for children only when used as directed by the doctor.
Q. Is Paracetamol an antibiotic?
No, Paracetamol is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Q. Can I take Paracetamol and ibuprofen together?
Ibuprofen and Paracetamol are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Q. How long does a Paracetamol take to work?
Paracetamol takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Q. What are the serious side effects of taking an excess of the Paracetamol?
Overdose of Paracetamole may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Phenylephrine
Q. Is it safe to use Phenylephrine?
Yes, Phenylephrine is safe for most of the patients. However, in some patients, it may cause side effects like nausea, vomiting, headache, fatigue, dizziness, dryness in the mouth, sleepiness and allergic reaction. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Q. Can the use of Phenylephrine cause dizziness?
Yes, the use of Phenylephrine can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines. Consult your doctor if the side effect persist or worsen.
Q. Can the use of Phenylephrine cause nausea and vomiting?
Yes, the use of Phenylephrine can cause nausea and vomiting. To avoid nausea one can take Phenylephrine with milk, food or with antacids. If vomiting occurs, drink plenty of water or other fluids. Talk to your doctor if vomiting persists. You should let your doctor know if you are unable to drink water and there are signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Avoid taking fatty or fried foods along with this medication. Do not take any other medicine without consulting your doctor.
Sodium Citrate
Q. Is sodium citrate ionic, covalent, or dissolve in water?
Sodium citrate is an ionic compound and dissolves in water. It does not contain covalent bonds
Q. Is Sodium Citrate a preservative, vegan or natural compound?
Yes, Sodium Citrate is a vegan compound used as a preservative
Q. Can I take Sodium Citrate with antibiotics?
No, avoid taking any two medications together and keep a gap of at least 1 hour between two drugs
Q. Does Sodium Citrate cause diarrhea?
Yes, long term use of Sodium Citrate can cause diarrhea
Q. Does Sodium Citrate cure cystitis and cancer?
Sodium Citrate is used to treat cystitis (inflammation of the urinary bladder) in women. It is not known to cause cancer
Q. Does Sodium Citrate contain gluten?
No, Sodium Citrate does not contain gluten
Q. Does sodium citrate bind calcium and have iodine in its structure?
No, sodium citrate does not contain iodine but it binds to the calcium in the blood and reduces blood clotting
Q. Is sodium citrate the same as citric acid?
Sodium citrate is an acid salt of citric acid
Q. Is Sodium Citrate safe?
Sodium Citrate is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.
