Manufacturer: Wockhardt Ltd
Salt Composition : Amikacin(250mg)
Vial of 2ml Injection
(Inclusive of all taxes)
Zekacin 250mg Injection works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional and should not be self-administered. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.
Zekacin 250mg Injection is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.
The plasma elimination half-life of amikacin is usually 2-3 hours in adults with normal renal function and is reported to range from 30-86 hours in adults with severe renal impairment. The mean serum clearance rate is about 100 mL/min and the renal clearance rate is 94 mL/min in subjects with normal renal function.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zekacin
Increased blood urea
Injection site reactions (pain, swelling, redness)
diarrhea from an infection with Clostridium difficile bacteria.
low amount of calcium in the blood.
dehydration.
a type of movement disorder called parkinsonism.
myasthenia gravis, a skeletal muscle disorder.
ringing in the ears.
disorder of nerve that controls hearing and balance.
Zekacin 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Consuming alcohol with Zekacin 250mg Injection does not cause any harmful side effects.
Zekacin 250mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Amikacin sulfate injection is indicated in the short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria, including Pseudomonas species, Escherichia coli, species of indole-positive and indole-negative Proteus, Providencia species, Klebsiella-Enterobacter-Serratia species, and ...
When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.
Zekacin Injection interacts with potent diuretics (ethacrynic acid or furosemide), which are used to increase the production of urine. Using Zekacin sulphate injection with diuretics may cause harmful effect to the ear. In addition, when diuretics are taken intravenously (into a vein), it may enhance the harmful effect of aminoglycoside by altering the level of antibiotic in the blood and tissue. The use of Zekacin sulphate injection with diuretics should be avoided.
There may be an interaction of Zekacin with beta-lactam antibotics such as penicillin, cephalosporins, which are used to treat bacterial infections. Using Zekacin parenterally with cephalosporins may increase the risk of drug-induced harmful effects on the kidney and increases the creatinine levels in the blood. In addition, when aminoglycosides or penicillins are given by a separate route, it may decrease the activity of the medicine in the blood.
Zekacin Injection may interact with cisplatin, ciclosporin, tacrolimus, which are used to treat cancer. Using Zekacin with cisplatin, ciclosporin or tacrolimus may increase the risk of additive effects. The use of Zekacin with these agents should be avoided. If required, patients should be monitored carefully.
Your doctor's guidelines may need to be followed while taking this medicine along with bisphosphonates, which are used to treat the loss of bone density. When Zekacin is used with bisphosphonates, it may decrease the calcium level in the blood.
Special instructions need to be followed while taking this medicine along with amphotericin B, vancomycin, clindamycine, paromomycin, cephaloridine bacitracin, viomycin, colistin, polymyxin B, or other aminoglycosides which are used to treat bacterial infection. The use of Zekacin with these medicines increases the risk of additive effects. The use of Zekacin with these agents should be avoided.
Your doctor's guidelines may need to be followed while taking this medicine along with opioid painkillers such as codeine, morphine, pethidine, fentanyl which are used to treat mild, moderate and severe pain. Inform or talk to your doctor if you are taking these medicines.
Special instructions need to be followed while taking this medicine along with indomethacin, which is used to treat pain and swelling. Indomethacin may increase the levels of Zekacin in neonates.
Zekacin Injection interacts with anesthetics or muscle-relaxing drugs (including ether, halothane, d-tubocurarine, succinylcholine, suxamethonium and decamethonium) which are used to induce paralysis and anesthesia. Using Zekacin intraperitoneally (inserted into the stomach) with anesthetics or muscle-relaxing drugs may cause neuromuscular blockade which may lead to slow and ineffective breathing. The intraperitoneal (inserted into the abdominal cavity) use of Zekacin with these medicines is not recommended.
There may be an interaction of Zekacin with thiamine (vitamin B1) which plays an important role in glucose metabolism, nerve, muscle, and heart functioning in the body. Thiamine (vitamin B1) may be destroyed by the reactive chemical part (sodium bisulfite) of Zekacin.
Zekacin Injection may interact with platinum compounds, which are used to treat cancer. Using Zekacin with platinum compounds may increase the risk of a drug-induced harmful effect on the kidney and ears.
Kindly do not self administer.
Store below 30°C
If you miss a dose of Zekacin 250mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Your doctor has prescribed Zekacin 250mg Injection to cure your infection and improve your symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle.
Your doctor may get regular blood, urine, or hearing tests while you are on this medication.
Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
Discontinue Zekacin 250mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. For how long can Zekacin 250mg Injection be taken?
The usual course of treatment with Zekacin 250mg Injection is about 7 to 10 days. However, your doctor will decide your dose depending on the condition you are being treated for. Continue taking Zekacin 250mg Injection in the dose and duration prescribed by the doctor to get maximum benefit. Do not alter the dose of the medicine on your own, consult your doctor first.
Q. Is Zekacin 250mg Injection safe?
Zekacin 250mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. How is Zekacin 250mg Injection administered?
Zekacin 250mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get the maximum benefit from Zekacin 250mg Injection.
Q. Can I take a higher than the recommended dose of this medicine?
No, Zekacin 250mg Injection should be taken in the recommended dose only. Overdose of Zekacin 250mg Injection can increase the risks of side effects. If you experience an increase in the severity of your symptoms during the treatment, please consult your doctor for re-evaluation.
