Zepdon 400mg Tablet (60'S)

Manufacturer: Cipla Ltd

Salt Composition : Raltegravir(400mg)


Zepdon 400mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow the instructions carefully, for all the medicines that you are given. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.


Some of the common side effects include insomnia (difficulty sleeping), headache, nausea, dizziness, and muscle pain. These are usually not serious but tell your doctor if they bother you or persist for a longer duration. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.


Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.


Basic Information

Mechanism Of Action

Zepdon 400mg Tablet is an antiviral medication. It prevents the multiplication of HIV virus in human cells. Thus stops the HIV virus from producing new viruses.


Pharmacokinets

Raltegravir is metabolized by uridine diphosphate-glucuronosyl-transferase (UGT) to a glucuronide metabolite, mainly by UGT1A1. The dose is eliminated in both the urine (32%) and feces (51%), with metabolite accounting for 23% and 0% in the urine and feces, respectively.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zepdon

Diarrhea

Dizziness

Fatigue

Headache

Insomnia (difficulty in sleeping)

Nausea

Abdominal pain

Abnormal dreams

Decreased appetite

Depression

Flatulence

Nightmares

Vomiting

Weakness

Contra Indications

aluminum hydroxide. aluminum hydroxide decreases levels of raltegravir by cation binding in GI tract. ...

aluminum hydroxide/magnesium carbonate. ...

aluminum hydroxide/magnesium trisilicate. ...

elvitegravir/cobicistat/emtricitabine/tenofovir DF. ...

magnesium supplement.

Pregnancy Related Information

Zepdon 400mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Product And Alcohol Interaction

Caution is advised when consuming alcohol with Zepdon 400mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Zepdon 400mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Raltegravir is used along with other medications to treat human immunodeficiency virus (HIV) infection in adults and children who weigh at least 4.5 lbs (2 kg). Raltegravir is in a class of medications called HIV integrase inhibitors. It works by decreasing the amount of HIV in the blood.

Interactions

Drug-Drug Interactions: RALTEGRAVIR may interact with antiviral/anti-HIV drug (atazanavir, ritonavir, tipranavir), anti-Tb drug (rifampicin), antidepressant (St John’s wort), iron supplements, antacids and anti-obesity drug (orlistat).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: RALTEGRAVIR should be used with caution in patients with mental health problems, bone problems, liver problems, skin problems, infections and muscle problems.

Drug-Drug Interactions Checker List:

ATAZANAVIR

RITONAVIR

TIPRANAVIR

RIFAMPICIN

IRON

ORLISTAT

ST JOHN'S WORT

Typical Dosage

Do not chew, crush or break it. Zepdon 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

Consult a doctor before taking any medicines.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Take it with or without food, preferably at the same time every day.

Do not skip any doses and finish the full course of treatment even if you feel better.

Do not take antacids or calcium supplements an hour before or two hours after taking Zepdon 400mg Tablet.

Your doctor may get regular blood tests done to monitor your blood cell counts and liver function during treatment with this medicine.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zepdon 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. Is raltegravir a protease inhibitor?

No. Raltegravir is an anti HIV drug. It does not have any known inhibitory effect on enzyme protease

Q. What is Zepdon 400mg Tablet used for?

Zepdon 400mg Tablet is used for the treatment for human immunodeficiency virus (HIV) infection

Q. How does Zepdon 400mg Tablet work?

How does Zepdon 400mg Tablet inhibit HIV viral replication?Zepdon 400mg Tablet works by inhibiting the action of an enzyme called integrase which is essential for the multiplication and survival of the virus (viral replication), thereby reducing HIV causing virus in the body.