Zestril 10mg Tablet (15'S)

Manufacturer: AstraZeneca

Salt Composition : Lisinopril(10mg)

₹297.10

Strip of 15 Tablet

(Inclusive of all taxes)


Zestril 10mg Tablet can be prescribed either alone or in combination with other medicines. It may be taken with or without food but try taking it at about the same time each day. It is important to continue taking it regularly even if you feel well or even if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This medicine is considered safe for long-term use.


Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor. The most common side effects of this medicine include decreased blood pressure, cough, increased potassium level, fatigue, weakness, and dizziness. Most of these are temporary and resolve with time. Talk to your doctor if any of the side effects bother you or do not go away.


Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.


Basic Information

Mechanism Of Action

Zestril 10mg Tablet is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Pharmacokinets

The accumulation half-life averages 12.6 hours despite a terminal serum half-life of approximately 40 hours. Steady state is attained after two daily doses (every 24 hours) in healthy volunteers. The drug is not metabolized but is eliminated via the kidneys.

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zestril

Decreased blood pressure

Cough

Increased potassium level in blood

Fatigue

Weakness

Dizziness

Contra Indications

Lisinopril is contraindicated in patients with hyperkalemia, a history of angioedema, renal failure with prior lisinopril use, bilateral renal artery stenosis, concomitant use with aliskiren in patients with diabetes mellitus, and during coadministration with a neprilysin inhibitor or within 36 hours of taking one.

Pregnancy Related Information

Zestril 10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product And Alcohol Interaction

It is unsafe to consume alcohol with Zestril 10mg Tablet.

Breast Feeding Related Information

Zestril 10mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Indications

Lisinopril is indicated for the treatment of acute myocardial infarction, hypertension in patients ≥6 years, and as an adjunct therapy for heart failure. A combination product with hydrochlorothiazide is indicated for the treatment of hypertension.

Interactions

DRUG-DRUG INTERACTIONS: LISINOPRIL may have interaction with heart failure medicines (sacubitril, valsartan), NSAIDs (aspirin, naproxen, indomethacin, ibuprofen), drugs used to treat erectile dysfunction (sildenafil), anti-gout medicines (allopurinol), anti-diabetic medicines (sitagliptin, metformin, insulin glargine), medicines used to treat oedema (furosemide), anti-hypertensive medication (aliskiren), medicines to treat depression (lithium), potassium supplements.

DRUG-FOOD INTERACTIONS: Maintain low salt and low-fat diet while taking LISINOPRIL. Avoid consuming potassium-rich foods such as potassium-containing salt substitutes or over-the-counter potassium supplements. Avoid smoking and alcohol consumption.

DRUG-DISEASE INTERACTIONS: LISINOPRIL may have interactions with angioedema (swelling), congestive heart failure (heart problems), anti-hemodialysis, low blood pressure, hyperkalemia (high levels of potassium in the body), liver diseases and kidney dysfunction.

Drug-Drug Interactions Checker List:

VALSARTAN

ASPIRIN

NAPROXEN

INDOMETHACIN

IBUPROFEN

SILDENAFIL

ALLOPURINOL

SITAGLIPTIN

METFORMIN

INSULIN GLARGINE

FUROSEMIDE

ALISKIREN

LITHIUM

POTASSIUM

SACUBITRIL

Typical Dosage

Do not chew, crush or break it. Zestril 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Storage Requirements

Store below 30°C

Effects Of Missed Dosage

If you miss a dose of Zestril 10mg Tablet, take it as soon as you remember. However, if it is nearly time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Zestril 10mg Tablet can make you feel dizzy for the first few days, so rise slowly if you have been sitting or lying down. You can also prefer taking it at bedtime to avoid dizziness throughout the day.

Let your doctor know about any cough, or throat irritation that does not go away.

It may increase the level of potassium in blood. Avoid taking potassium supplements and potassium-rich foods such as banana and broccoli.

Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zestril 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

FAQs

Q. What is Zestril 10mg Tablet? What is it used for?

Zestril 10mg Tablet belongs to a group of medicines known as angiotensin-converting enzyme (ACE) inhibitors. It is used to treat high blood pressure (hypertension). It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it helps to lower the blood pressure and thus reduces the risk of heart attack and stroke.

Q. What should I tell my doctor before taking Zestril 10mg Tablet?

Before taking Zestril 10mg Tablet you must tell your doctor if you are allergic to Zestril 10mg Tablet or any of its ingredients. You must tell the doctor if you have any problems related to heart, liver, kidneys (if you are on dialysis) or blood, such as a low white blood cell count (neutropenia or agranulocytosis). Inform your doctor if you have diabetes, irregular blood pressure or if you have recently had diarrhea or vomiting. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Consult your doctor before taking Zestril 10mg Tablet if you are planning to conceive, if you are pregnant or breastfeeding to avoid any harmful effects on the baby.

Q. What time of the day should I take Zestril 10mg Tablet?

Zestril 10mg Tablet should be taken at the same time each day to reduce the chances of a missed dose. Take it in the dose and duration prescribed by the doctor. Your doctor may advise you to take your first dose before bedtime, because it can make you dizzy. After the first dose, if you do not feel dizzy, you may take Zestril 10mg Tablet at any time of the day. Your dose will depend on the condition you are being treated for and therefore, it will vary from person to person. If you experience any side effects while taking Zestril 10mg Tablet, please consult your doctor.

Q. I feel better after taking Zestril 10mg Tablet, can I stop taking it?

No, continue taking Zestril 10mg Tablet even if you feel better and your blood pressure is under control. Stopping Zestril 10mg Tablet suddenly may cause your blood pressure to increase and your chances of stroke or heart attack may rise. Usually once you start taking any medicine for controlling blood pressure, you have to continue taking it life long unless you cannot tolerate it.