Zidine 300mg Tablet (60'S)

Manufacturer: Emcure Pharmaceuticals Ltd

Salt Composition : Zidovudine(300mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Zidine 300mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.


Zidine 300mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.


Common side effects of this medicine include headache, nausea, vomiting, stomach pain, fatigue, diarrhea, and rash. These are usually not serious but tell your doctor if they bother you or will not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.


Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.



Basic Information

Mechanism Of Action

ZDV is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA and therefore decreases replication of the virus. Zidovudine was first described in 1964.


Pharmacokinets

Zidovudine is rapidly and extensively absorbed following oral administration. The mean half-life is approximately ih. The drug is capable of crossing the blood-brain barrier resulting in antiviral concentrations within the cerebrospinal

Side Effects

Headache

Nausea

Vomiting

Stomach pain

Fatigue

Diarrhea

Rash

Contra Indications

increased blood acidity due to high levels of lactic acid.

anemia.

low levels of a type of white blood cell called neutrophils.

a disease with shrinking and weaker muscles called myopathy.

toxic amblyopia, a loss of vision.

liver problems.

severe liver disease.

muscle inflammation.


Pregnancy Related Information

Zidine 300mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Zidine 300mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Zidine 300mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.


Indications

HIV-1 infection, in combination with other antiretroviral agents. Prevention of maternal-fetal HIV-1 transmission.


Interactions

Some products that may interact with this drug include: orlistat, probenecid, ribavirin, stavudine, drugs that may suppress bone marrow function (such as ganciclovir, dapsone, trimethoprim, chemotherapy including doxorubicin, vincristine).


Typical Dosage

Do not chew, crush or break it. Zidine 300mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Zidine 300mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines

Expert Advice

In combination with other medicines, it is used for the treatment of HIV infections.

Take it with food, as this increases the absorption of the medicine into the body.

Zidine 300mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.

You may still develop infections or other illnesses associated with viral infection while taking this medication.

You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.

During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zidine 300mg Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. What is Zidine 300mg Tablet? What is it used for?

Zidine 300mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Q. Is Zidine 300mg Tablet safe?

Zidine 300mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. How does Zidine 300mg Tablet work?

Zidine 300mg Tablet works by blocking the function of an enzyme, called reverse transcriptase, which is responsible for the HIV replication process. This helps to reduce the level of HIV in the blood.

Q. How should I take Zidine 300mg Tablet?

Zidine 300mg Tablet should be taken in the dose and duration advised by the doctor. This medicine may be taken with or without food but it is better to be taken at a fixed time of the day to avoid the chances of missing a dose.