Manufacturer: Intas Pharmaceuticals Ltd
Salt Composition : Doxorubicin(Plain)(50mg)
It is given as a drip or infusion vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.
The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.
Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.
Zodox 50mg Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.
Up to several weeks after administration, significant concentrations of doxorubicin have been found in haematopoietic cells and in several other tissues. The maximum cellular doxorubicin concentrations reached in vivo remain significantly below those at which all clonogenic leukaemic cells are killed in vitro.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zodox
Vomiting
Allergic reaction
Nausea
Mouth sore
Hair loss
Stomach pain
Eye disorder
Increased thirst
Arrhythmia (irregular heartbeats)
Nail disorder
Severe myocardial insufficiency [see Warnings and Precautions (5.1)]
Recent (occurring within the past 4–6 weeks) myocardial infarction [see Warnings and Precautions (5.1)]
Severe persistent drug-induced myelosuppression [see Warnings and Precautions (5.4)]
Zodox 50mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Zodox 50mg Injection. Please consult your doctor.
Zodox 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Doxorubicin may be used to treat soft tissue and bone sarcomas and cancers of the breast, ovary, bladder, and thyroid. It is also used to treat acute lymphoblastic leukemia, acute myeloblastic leukemia, Hodgkin lymphoma, and small cell lung cancer.
Some products that may interact with this drug include: digoxin, progesterone, streptozocin, stavudine, trastuzumab, zidovudine. Other medications can affect the removal of doxorubicin from your body, which may affect how doxorubicin works.
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose, please consult your doctor.
Consult a doctor before taking any medicines.
Zodox 50mg Injection is given as an injection into the vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
Inform your doctor if you experience fever, chills, shortness of breath and swelling of face or lips.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How does doxorubicin work?
Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medications called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cells. This helps treat the cancer.
Q. Is doxorubicin a vesicant?
Yes doxorubicin is a vesicant (irritant).
