Manufacturer: Elder Pharmaceuticals Ltd
Salt Composition : Cefoperazone(500mg), Sulbactam(500mg)
Zofactum 500 mg/500 mg Injection should only be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine.
Some common side effects of this medicine are nausea, vomiting, diarrhea, indigestion, etc. If any of the side effects get aggravated, you must consult your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. You must take adequate rest for a faster recovery, also take a healthy diet and drink plenty of water. Your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Zofactum 500 mg/500 mg Injection acts by killing the bacteria responsible for infections. However, bacteria make an enzyme (beta-lactamases), which can destroy cefoperazone. Sulbactam inactivates this enzyme and hence helps cefoperazone to function optimally.
The human pharmacology of cefoperazone is similar to cephazolin in terms of serum concentrations, half-life, protein binding, and apparent volume of distribution, but markedly different in terms of biliary and renal excretion.Sulbactam, a new beta-lactamase inhibitor, has pharmacokinetic characteristics in humans similar to those of ampicillin and amoxicillin. Its half-life in humans is approximately 1 h.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zosul
Diarrhea
Abnormal liver function tests
Allergic reaction
Anemia (low number of red blood cells)
If you are suffering from any of the following diseases, you should not take Cefoperazone + Sulbactam unless your doctor advises you to do so -
Allergy
Kidney Disease
Zofactum 500 mg/500 mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Consuming alcohol while taking Zofactum 500 mg/500 mg Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Zofactum 500 mg/500 mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
CEFOPERAZONE+SULBACTAM belongs to the group of medicines called antibiotics used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections.
CEFOPERAZONE+SULBACTAM may have interaction with a diuretic (furosemide), anticoagulants (warfarin), other antibiotics (gentamicin).
Kindly do not self administer.
Store below 30°C
If you miss a dose of Zofactum 500 mg/500 mg Injection, please consult your doctor.
Consult a doctor before taking any medicines.
You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance.
Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect. Taking probiotics along with Zofactum 500 mg/500 mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
Stop taking Zofactum 500 mg/500 mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. What is Zofactum 500 mg/500 mg Injection?
Zofactum 500 mg/500 mg Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic which works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.
Q. How long does Zofactum 500 mg/500 mg Injection takes to work?
Usually, Zofactum 500 mg/500 mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.
Q. What if I don't get better after using Zofactum 500 mg/500 mg Injection?
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
