Zomibet 2mg (Injection)


Zomibet 2mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.


Fatigue, nausea, vomiting, and loss of appetite are some common side effects of this medicine. You may be advised to drink plenty of fluids every day during the treatment. You should not drive or operate machinery as medicine may cause tiredness and dizziness. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.


Before taking Zomibet 2mg Injection, consult with your doctor if you have any liver, kidney, heart disease or bleeding problem.  It is important to consult a doctor if you develop symptoms like memory loss or trouble in thinking. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Basic Information

Mechanism Of Action

Zomibet 2mg Injection is an anti-cancer medication. It works by blocking or slowing the breakdown of proteins in cells. As a result, there is an increase in a number of proteins in the cancer cells leading to their death.


Pharmacokinets

The pharmacokinetic profile of intravenous bortezomib is characterized by a two-compartment model with a rapid initial distribution phase followed by a longer elimination phase and a large volume of distribution. Bortezomib is available for subcutaneous and intravenous administration.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zomibet

Low blood platelets

Fatigue

Peripheral neuropathy (tingling and numbness of feet and hand)

Psychiatric disturbances

Nausea

Vomiting

Loss of appetite

Fever

Anemia (low number of red blood cells)

Diarrhea

Decreased appetite

Decreased white blood cell count (neutrophils)

Constipation

Contra Indications

diabetes.

dehydration.

decreased blood platelets.

low levels of a type of white blood cell called neutrophils.

a painful condition that affects the nerves in the legs and arms called peripheral neuropathy.

pulmonary hypertension.

chronic heart failure.

Pregnancy Related Information

Zomibet 2mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.


Product And Alcohol Interaction

Zomibet 2mg Injection may cause excessive drowsiness with alcohol.


Breast Feeding Related Information

Zomibet 2mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Bortezomib is indicated for the treatment of adult patients with multiple myeloma or mantle cell lymphoma.


Interactions

Bortezomib was synergistic with dexamethasone in dexamethasone-sensitive leukemia cells, and additive with vincristine, asparaginase, cytarabine, and doxorubicin. The anti-leukemic activity of bortezomib was also additive with geldanamycin and HA14.


Typical Dosage

Kindly do not self administer.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Zomibet 2mg Injection, please consult your doctor.


Effects Of Overdose

 Consult a doctor before taking any medicines.

Expert Advice

Zomibet 2mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.

Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet. 

How To Use

Zomibet 2mg Injection is given as an injection into veins or skin under the supervision of a healthcare professional.

Do not skip any dose and complete the course as suggested by your doctor.

Use an effective method of birth control to avoid pregnancy while taking this medication.

You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.

Inform your doctor immediately if you experience coughing, shortness of breath and swelling of feet. 

FAQs

Q. When should I call my doctor right away?

Get medical help right away if you have muscle cramping, muscle weakness, confusion, visual loss or disturbances, blindness, seizures, headaches, shortness of breath, swelling of your feet or changes in your heartbeat, high blood pressure, tiredness, fainting, coughing and breathing difficulties or tightness in the chest.

Q. How will you know that Zomibet 2mg Injection is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

Q. What precautions should I take to reduce the chances of getting infected during treatment with Zomibet 2mg Injection?

Since Zomibet 2mg Injection lowers the number of white blood cells and platelets in your blood, it puts you at risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.

Q. Can Zomibet 2mg Injection be used during pregnancy?

No, this medicine should not be used during pregnancy as it can harm your unborn baby. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 3 months after the last dose of Zomibet 2mg Injection.