Zoryl 2mg Tablet (15'S)

Manufacturer: Intas Pharmaceuticals Ltd

Salt Composition : Glimepiride(2mg)

Prescription
Prescription Required: Consult the Doctor & Get Your ePrescription

Zoryl 2 Tablet may be used alone or along with other medicines. It should be taken just before or with the first meal of the day. Take it regularly at the same time each day to get the maximum benefit. Your doctor will decide what dose is best for you and this may change from time to time according to your blood sugar levels.


Basic Information

Mechanism Of Action

Glimepiride lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally.

Pharmacokinets

Glimepiride is completely metabolized by oxidative biotransformation after either an IV or oral dose. The major metabolites are the cyclohexyl hydroxy methyl derivative (M1) and the carboxyl derivative (M2). Cytochrome P450 2C9 has been shown to be involved in the biotransformation of glimepiride to M1.


Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoryl

Hypoglycemia (low blood glucose level)

Headache

Nausea

Dizziness


Contra Indications

low blood sugar.

pituitary hormone deficiency.

a condition where the adrenal glands produce less hormones called Addison's disease.

glucose-6-phosphate dehydrogenase (G6PD) deficiency.

hepatic porphyria.

a type of blood disorder where the red blood cells burst called hemolytic anemia.


Pregnancy Related Information

Zoryl 2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

It is unsafe to consume alcohol with Zoryl 2 Tablet.


Breast Feeding Related Information

Zoryl 2 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Zoryl 2 Tablet


Indications

Glimepiride is used to treat high blood sugar levels caused by type 2 diabetes. It may be used alone, or in combination with insulin or another oral medicine such as metformin. In type 2 diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly.

Interactions

Interactions. Medications that affect glucose control may interact with glimepiride. Insulin and other antidiabetic medications work with glimepiride to produce a combined hypoglycemic effect. Together, these drugs may lower blood sugar to a level that results in hypoglycemia.

Typical Dosage

Do not chew, crush or break it. Zoryl 2 Tablet is to be taken with food.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

You should skip a dose of Zoryl 2 Tablet if a meal is skipped, and add a dose of medicine if you eat an extra meal.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Zoryl 2 Tablet helps decrease high blood sugar level and avoid long-term complications of diabetes.

Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.

Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.

Monitor your blood sugar level regularly while you are taking this medicine.

Be careful while driving or operating machinery until you know how Zoryl 2 Tablet affects you.

It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.

Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).


How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zoryl 2 Tablet is to be taken with food.


FAQs

Q. Does Zoryl 2 Tablet make you sleepy?

Zoryl 2 Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.

Q. Is Zoryl 2 Tablet safe for kidneys?

Zoryl 2 Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Zoryl 2 Tablet is principally eliminated by the kidneys.

Q. Does Zoryl 2 Tablet cause memory loss?

No, it is not known that Zoryl 2 Tablet causes memory loss. However, the use of Zoryl 2 Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.

Q. Who should not take Zoryl 2 Tablet?

Zoryl 2 Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Zoryl 2 Tablet.