Manufacturer: Alkem Laboratories Ltd
Salt Composition : Chlorpheniramine Maleate(2mg), Paracetamol(125mg), Phenylephrine(2.5mg)
Bottle of 60ml Suspension
(Inclusive of all taxes)
This medication may be taken with or without food preferably one hour before you travel. Take it in a dose and duration as advised by the doctor. But, before taking it, inform doctor if you are suffering from depression and taking its medicines.Dizziness may occur as its side effect, so do not drive or do anything that requires mental focus. You should avoid drinking alcohol while taking this medicine, as it may cause excessive sleepiness.
Zukamin Cold Suspension is an antihistamine that works by blocking the action of histamine in the body. It is used for relieving symptoms of sinus pressure, sinus congestion, runny nose, itching of the throat and nose, watery eyes, and sneezing due to upper respiratory infections, hay fever, and allergies.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration [1, 8]. It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Zukamin Cold Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Zukamin Cold
Dryness in mouth
Sleepiness
Drowsiness
Loss of appetite
Nausea
Insomnia (difficulty in sleeping)
Constipation
Vomiting
Headache
High blood pressure
Arrhythmia (irregular heartbeats)
Blurred vision
Breathlessness
Itching
Restlessness
Reflex bradycardia
Excitation
Epigastric pain
Neck pain
Tremors
Hypertensive crisis
Eye pain
Stinging in the eyes
Photophobia
Conjunctival sensitivity
Preterm and low birth weight infants
Fainting
Myocardial infarction
Subarachnoid hemorrhage
overactive thyroid gland.
closed angle glaucoma.
high blood pressure.
stenosing peptic ulcer.
blockage of the stomach or intestine.
blockage of the urinary bladder.
enlarged prostate.
an inability to completely empty the bladder.
PRESCRIBE THE CHILD'S DOCTOR
Use with caution
Below 5years: Contraindicated
CHLORPHENIRAMINE+PARACETAMOL+PHENYLEPHRINE belongs to the class of medication called 'cough and cold medications' primarily used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
If you use other drugs or over the counter products at the same time, the effects of Zukamin Cold Suspension may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Zukamin Cold Suspension may interact with the following drugs and products:
Alcohol
Antipsychotics
Decongestants
Digoxin
High blood pressure medicines
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Leflunomide
Phenytoin
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Zukamin Cold Suspension is to be taken with food.
Store below 30°C
Do not panic. Unless your child’s doctor has advised a specific regime for your child, you can give the missed dose as soon as you remember it. Skip the missed dose if it’s almost the time for the next dose. Follow the prescribed dosing schedule and do not give a double dose to catch up with the missed dose.
Consult a doctor before taking any medicines.
Chlorpheniramine Maleate
Avoid driving or operating dangerous machinery as it may decrease alertness.
Avoid consuming alcohol when taking the Chlorpheniramine Maleate, as it may cause excessive sleepiness or drowsiness.
Paracetamol
Paracetamol should be taken with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
Inform your doctor if you have liver disease as your dose may need to be adjusted.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.
Phenylephrine
Oral phenylephrine should be taken with food
Phenylephrine can make you restless, so don't take it too close to bedtime
Do not use this medicine without doctor's advice if you are pregnant or breast feeding
Smoking may worsen the effect; therefore use of tobacco should be avoided.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Zukamin Cold Suspension is to be taken with food.
Chlorpheniramine Maleate
Q. Does chlorpheniramine or chlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?
Chlorpheniramine causing these side effects is common or rare. Always consult your doctor, if you experience any of these side effects
Q. Is chlorpheniramine like Benadryl?
No, chlorpheniramine is different from Benadryl
Q. Is chlorpheniramine prescription?
Yes, it is available with doctor’s prescription only
Q. Can I take chlorpheniramine or chlorpheniramine maleate with Panadol/ cetirizine /Zyrtec/ Allegra/ warfarin/ diphenhydramine/ ibuprofen/Claritin/guaifenesin/Benadryl?
Yes, but taking other medicines may alter the effects of chlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Q. Does chlorpheniramine contain aspirin?
No, it does not contain aspirin in it. Chlorpheniramine is a different drug than aspirin.
Paracetamol
Q. What if I vomit after taking Paracetamol?
If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.
Q. When will I feel better after taking the Paracetamol?
Usually, you will start feeling better after about half an hour of taking a Paracetamol.
Q. How often can I take the Paracetamol?
You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.
Q. Does Paracetamol make babies sleepy?
No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.
Q. Is Paracetamol safe for children?
Paracetamol is considered safe for children only when used as directed by the doctor.
Q. Is Paracetamol an antibiotic?
No, Paracetamol is not an antibiotic. It works as a painkiller and fever-reducing medicine.
Q. Can I take Paracetamol and ibuprofen together?
Ibuprofen and Paracetamol are safe medicines, but both should not be used together. Consult your doctor if you are not sure.
Q. How long does a Paracetamol take to work?
Paracetamol takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.
Q. What are the serious side effects of taking an excess of the Paracetamol?
Overdose of Paracetamole may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Phenylephrine
Q. Is it safe to use Phenylephrine?
Yes, Phenylephrine is safe for most of the patients. However, in some patients, it may cause side effects like nausea, vomiting, headache, fatigue, dizziness, dryness in the mouth, sleepiness and allergic reaction. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.
Q. Can the use of Phenylephrine cause dizziness?
Yes, the use of Phenylephrine can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines. Consult your doctor if the side effect persist or worsen.
Q. Can the use of Phenylephrine cause nausea and vomiting?
Yes, the use of Phenylephrine can cause nausea and vomiting. To avoid nausea one can take Phenylephrine with milk, food or with antacids. If vomiting occurs, drink plenty of water or other fluids. Talk to your doctor if vomiting persists. You should let your doctor know if you are unable to drink water and there are signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Avoid taking fatty or fried foods along with this medication. Do not take any other medicine without consulting your doctor.
