Manufacturer: Alkem Laboratories Ltd
Salt Composition : Chlorpheniramine Maleate(2mg), Paracetamol(325mg), Phenylephrine(10mg)
Using this medicine may cause a few common side effects such as nausea, vomiting, sleepiness, dizziness, and headache. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the side effects. In general, you should try to use the smallest amount necessary to control your symptoms.Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. To make sure it is safe, you should let your doctor know all the other medicines you are taking. Also, tell your doctor if you have any problems with the liver or kidneys. Avoid consumption of alcohol while on treatment with this medicine as it may increase the chance of some side effects. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Zukarest Tablet is a combination of three medicines: Chlorpheniramine, Paracetamol / Acetaminophen and Phenylephrine. This combination helps to relieve symptoms of cold like runny nose, watery eyes, fever and headache. Chlorpheniramine is an antiallergic.
Chlorpheniramine has a serum half-life of approximately 20 hours in adults, and elimination from the body is primarily by metabolism to monodesmethyl and didesmethyl compounds. The half-life is increased in the presence of renal dysfunction and decreased in children.
It distributes rapidly and evenly throughout most tissues and fluids and has a volume of distribution of approximately 0.9L/kg. 10 to 20% of the drug is bound to red blood cells. Paracetamol is extensively metabolised (predominantly in the liver), the major metabolites being the sulphate and glucuronide conjugates.
Phenylephrine is readily and completely absorbed from the gastro-intestinal tract after oral administration [1, 8]. It is subject to extensive presystemic metabolism in the gut wall and therefore has a systemic bioavailability of approximately 40% relative to intravenous dosing.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zukarest
Nausea
Vomiting
Allergic reaction
Sleepiness
Headache
Dizziness
overactive thyroid gland.
closed angle glaucoma.
high blood pressure.
stenosing peptic ulcer.
blockage of the stomach or intestine.
blockage of the urinary bladder.
enlarged prostate.
an inability to completely empty the bladder.
Zukarest Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Zukarest Tablet.
Zukarest Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Use with caution
Below 9years: Contraindicated
CHLORPHENIRAMINE+PARACETAMOL+PHENYLEPHRINE belongs to the class of medication called 'cough and cold medications' primarily used to treat symptoms of the common cold and allergies like sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes.
If you use other drugs or over the counter products at the same time, the effects of Zukarest Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Zukarest Tablet may interact with the following drugs and products:
Alcohol
Antipsychotics
Decongestants
Digoxin
High blood pressure medicines
Interfere with certain laboratory tests
Juxtapid mipomersen
Ketoconazole
Leflunomide
Phenytoin
Do not chew, crush or break it. Zukarest Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Zukarest Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Zukarest Tablet helps relieve symptoms of cold and flu such as headache, sore throat, runny nose, muscular pain, and fever.
It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how it affects you.
Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness.
Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zukarest Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Zukarest Tablet?
Zukarest Tablet is a combination of three medicines: Chlorpheniramine, Paracetamol / Acetaminophen and Phenylephrine. This combination helps to relieve symptoms of cold like runny nose, watery eyes, fever and headache. Chlorpheniramine is an antiallergic. It relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Phenylephrine is a decongestant which narrows the small blood vessels and provides relief from congestion or stuffiness in the nose.
Q. Is it safe to use Zukarest Tablet?
Yes, Zukarest Tablet is safe in most patients. However, in some patients it may cause common side effects like nausea, vomiting, allergic reaction, sleepiness, headache and other uncommon or rare side effects. Inform the doctor if you experience any persistent problem while taking this medicine.
Q. Can I stop taking Zukarest Tablet when I am relieved of my symptoms?
Zukarest Tablet is usually used for short term and can be discontinued when your symptoms are relieved. However, continue taking this medicine if your doctor has advised you to do so.
Q. Can the use of Zukarest Tablet cause dizziness?
Yes, the use of Zukarest Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
Q. Can the use of Zukarest Tablet cause damage to liver?
Zukarest Tablet is usually safe when taken according to the recommended dose. However, an overdose of Zukarest Tablet can damage your liver. Avoid drinking alcohol, while taking this medicine as it may increase your risk of liver damage.
Q. What is the recommended storage condition for the Zukarest Tablet?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
