Manufacturer: Zydus Cadila
Salt Composition : Febuxostat(40mg)
Zurig 40 Tablet can be taken with or without food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because of the formation of more crystals in your joints. You can help yourself by making some changes to your diet (eg. avoiding alcohol and non-vegetarian foods) and drinking plenty of fluids.
Some of the common side effects of this medicine are headache, diarrhea, nausea, and skin rash. You may experience a temporary increase in the gout symptoms (rapid onset of severe pain, warmth, and redness in the joint) when you first start taking the medicine. However, do not stop taking the medicine. Your doctor may suggest some painkillers and additional medicines to help reduce or prevent these symptoms. Tell your doctor right away if you get any symptoms of liver disease like persistent nausea, dark urine, or yellowing of the eyes or skin.
Before taking this medicine, let your doctor know if you have any heart problems, stroke, thyroid problems, or kidney or liver problems. If you are pregnant or breastfeeding, this medicine is best avoided. Check with your doctor. You will need regular blood tests while taking this medicine to check that your liver is working properly.
The primary mechanism of action of febuxostat evaluated in trials was the inhibition of xanthine oxidase, evidenced by the increase in serum and urine xanthine concentrations, decrease in serum and urine uric acid levels, and lack of significant reduction in total purine synthesis
In healthy subjects, the pharmacokinetic parameters of febuxostat after multiple oral dose administration include an oral availability of about 85 %, an apparent oral clearance (CL/F) of 10.5 ± 3.4 L/h and an apparent volume of distribution at steady state (V ss/F) of 48 ± 23 L.
Diarrhea
Headache
Increased liver enzymes
Nausea
Skin rash
Gout flares
chronic heart failure.
a disorder of the blood vessels of the brain.
hardening of the arteries due to plaque buildup.
abnormal liver function tests.
chronic kidney disease stage 4
Zurig 40 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Zurig 40 Tablet. Please consult your doctor.
Zurig 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Febuxostat oral tablet is used to treat hyperuricemia (constantly high levels of uric acid) in adults who have gout. It helps decrease your symptoms of gout. Symptoms of gout include pain, swelling, redness, heat, soreness, and stiffness in certain joints
secondary hyperuricemia.
CV disease.
renal dysfunction.
hepatic impairment
Do not chew, crush or break it. Zurig 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Zurig 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines
Your doctor has prescribed Zurig 40 Tablet to reduce episodes of gout attack.
Take it at the same time every day, with or without food.
Take plenty of fluids (2-3 litres) daily while on Zurig 40 Tablet.
When you first start taking this medicine, you might have more gout attacks. Do not stop Zurig 40 Tablet on having an acute attack of gout as that could make an attack worse.
Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever, or swelling of limbs or face.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zurig 40 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What is Zurig 40 Tablet used for?
Zurig 40 Tablet is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain, and heat in one or more joints.
Q. What are the side effects of Zurig 40 Tablet?
Zurig 40 Tablet may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Zurig 40 Tablet include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.
Q. How long should I take Zurig 40 Tablet?
The dose and duration of Zurig 40 Tablet vary from person to person and are decided by your doctor. It may take several months before Zurig 40 Tablet begins to prevent gout attacks. Do not stop taking Zurig 40 Tablet without the advice of your doctor even if you feel better.
Q. What is the best time to take Zurig 40 Tablet?
Zurig 40 Tablet is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Zurig 40 Tablet in the body. You can take this medicine with or without food.
