Zurig 80mg Tablet (30'S)

Manufacturer: Zydus Cadila

Salt Composition : Febuxostat(80mg)


Zurig 80 Tablet can be taken with or without food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because of the formation of more crystals in your joints. You can help yourself by making some changes to your diet (eg. avoiding alcohol and non-vegetarian foods) and drinking plenty of fluids.



Basic Information

Mechanism Of Action

The primary mechanism of action of febuxostat evaluated in trials was the inhibition of xanthine oxidase, evidenced by the increase in serum and urine xanthine concentrations, decrease in serum and urine uric acid levels, and lack of significant reduction in total purine synthesis

Pharmacokinets

In healthy subjects, the pharmacokinetic parameters of febuxostat after multiple oral dose administration include an oral availability of about 85 %, an apparent oral clearance (CL/F) of 10.5 ± 3.4 L/h and an apparent volume of distribution at steady state (V ss/F) of 48 ± 23 L.

Side Effects

Diarrhea

Headache

Increased liver enzymes

Nausea

Skin rash

Gout flares

Contra Indications

chronic heart failure.

a disorder of the blood vessels of the brain.

hardening of the arteries due to plaque buildup.

abnormal liver function tests.

chronic kidney disease stage 4 

Pregnancy Related Information

Zurig 80 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.


Product And Alcohol Interaction

Caution is advised when consuming alcohol with Zurig 80 Tablet. Please consult your doctor.


Breast Feeding Related Information

Zurig 80 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.


Indications

Febuxostat oral tablet is used to treat hyperuricemia (constantly high levels of uric acid) in adults who have gout. It helps decrease your symptoms of gout. Symptoms of gout include pain, swelling, redness, heat, soreness, and stiffness in certain joints

Interactions

secondary hyperuricemia.

CV disease.

renal dysfunction.

hepatic impairment

Typical Dosage

Do not chew, crush or break it. Zurig 80 Tablet may be taken with or without food, but it is better to take it at a fixed time.


Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose of Zurig 80 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.


Effects Of Overdose

Consult a doctor before taking any medicines.


Expert Advice

Your doctor has prescribed Zurig 80 Tablet to reduce episodes of gout attack.

Take it at the same time every day, with or without food.

Take plenty of fluids (2-3 litres) daily while on Zurig 80 Tablet.

When you first start taking this medicine, you might have more gout attacks. Do not stop Zurig 80 Tablet on having an acute attack of gout as that could make an attack worse.

Do not consume alcohol while taking this medicine as it may cause your gout to flare up.

Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever, or swelling of limbs or face.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zurig 80 Tablet may be taken with or without food, but it is better to take it at a fixed time.


FAQs

Q. What is Zurig 80 Tablet used for?

Zurig 80 Tablet is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain, and heat in one or more joints.

Q. What are the side effects of Zurig 80 Tablet?

Zurig 80 Tablet may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Zurig 80 Tablet include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.

Q. How long should I take Zurig 80 Tablet?

The dose and duration of Zurig 80 Tablet vary from person to person and are decided by your doctor. It may take several months before Zurig 80 Tablet begins to prevent gout attacks. Do not stop taking Zurig 80 Tablet without the advice of your doctor even if you feel better.

Q. What is the best time to take Zurig 80 Tablet?

Zurig 80 Tablet is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Zurig 80 Tablet in the body. You can take this medicine with or without food.