Zybirra 250mg Tablet (120'S)

Manufacturer: Zydus Cadila

Salt Composition : Abiraterone Acetate(250mg)


Zybirra 250mg Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.



Basic Information

Mechanism Of Action

Zybirra 250mg Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.

Pharmacokinets

 The pharmacokinetic results for abiraterone acetate showed a mean for the maximum plasma concentration (Cmax) of 54.67 ± 68.30 pg/ml, and a median time to maximum concentrations (tmax) of 5.53 h (range 2.67–35.00 h).

Side Effects

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Edema (swelling)

Vomiting

Decreased potassium level in blood

Decreased white blood cell count

Fatigue

Increased liver enzymes

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Cough

Hypercholesterolemia (high cholesterol)

Joint swelling

Increased levels of blood fat

Altered blood sugar level

Contra Indications

Abiraterone acetate is contraindicated in pregnancy and should be used with caution in patients with cardiac disease. Because of the potential increase in blood pressure and fluid retention, abiraterone acetate should be used with caution in patients with heart failure and ventricular arrhythmias.


Pregnancy Related Information

Zybirra 250mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.


Product And Alcohol Interaction

It is not known whether it is safe to consume alcohol with Zybirra 250mg Tablet. Please consult your doctor.


Breast Feeding Related Information

Zybirra 250mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.


Indications

Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.


Interactions

A product that may interact with this drug is: radium Ra 223. Other medications can affect the removal of abiraterone from your body, which may affect how abiraterone works. Examples include rifamycins (such as rifabutin), drugs used to treat seizures (such as carbamazepine, phenytoin, phenobarbital, primidone), St.


Typical Dosage

 Do not chew, crush or break it. Zybirra 250mg Tablet is to be taken empty stomach.

Storage Requirements

Store below 30°C


Effects Of Missed Dosage

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Effects Of Overdose

Consult a doctor before taking any medicines.

Expert Advice

Zybirra 250mg Tablet treats prostate cancer that has spread to other parts of the body.

It is usually taken with another medicine called prednisolone to reduce unwanted side effects.

It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.

Always use effective birth control measures to prevent pregnancy while taking this medicine.

Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

How To Use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zybirra 250mg Tablet is to be taken empty stomach.


FAQs

Q. Can Zybirra 250mg Tablet cure prostate cancer?

Zybirra 250mg Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Zybirra 250mg Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Zybirra 250mg Tablet.