Manufacturer: Zydus Cadila
Salt Composition : Bicalutamide(50mg)
Zyluta 50mg Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Anemia (low number of red blood cells) is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects which require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.
Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
Zyluta 50mg Tablet blocks the effect of the natural male hormones on the growth of prostate cells. Zyluta 50mg Tablet also blocks the undesired effects of androgens in females such as excessive hair growth and acne.
Bicalutamide and its metabolites are eliminated in urine, feces, and bile, mainly in the form of conjugates. The pharmacokinetics of bicalutamide are not influenced by food, age, body weight, renal impairment, or mild-to-moderate hepatic impairment, but ethnicity may influence its pharmacokinetics in some cases.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zyluta
Anemia (low number of red blood cells)
Rash
Abdominal pain
Constipation
Decreased appetite
Dizziness
Hot flashes
Nausea
Weakness
Nocturia (increased urge to urinate during the night)
Edema (swelling)
contraindicated in any patient who has shown a hypersensitivity reaction to the drug or any of the tablet's components. Hypersensitivity reactions including angioneurotic edema and urticaria have been reported.
Zyluta 50mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
It is not known whether it is safe to consume alcohol with Zyluta 50mg Tablet. Please consult your doctor.
Information regarding the use of Zyluta 50mg Tablet during breastfeeding is not available. Please consult your doctor.
Bicalutamide is indicated in combination with a luteinizing hormone-releasing hormone (LHRH) agonist for the treatment of Stage D2 metastatic carcinoma of the prostate. Build, train, & validate predictive machine-learning models with structured datasets.
Drug-Drug Interactions: BICALUTAMIDE may have interaction with medicine for stomach disorders (cisapride), anti-allergic drugs (astemizole, terfenadine), heart-related drugs (procainamide, amiodarone, sotalol, quinidine), antibiotic (moxifloxacin), opioid painkiller (methadone), blood thinner (warfarin), immunosuppressant (ciclosporin), antacid (cimetidine), antifungal (ketoconazole).
Drug-Food Interactions: BICALUTAMIDE may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with BICALUTAMIDE as it may increase concentrations of BICALUTAMIDE and cause more adverse effects.
Drug-Disease Interactions: If you have diabetes, liver or heart problems, inform your doctor before taking BICALUTAMIDE.
Drug-Drug Interactions Checker List:
CISAPRIDE
ASTEMIZOLE
TERFENADINE
PROCAINAMIDE
AMIODARONE
SOTALOL
QUINIDINE
MOXIFLOXACIN
METHADONE
WARFARIN
CICLOSPORIN
CIMETIDINE
KETOCONAZOLE
Store below 30°C
If you miss a dose of Zyluta 50mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed Zyluta 50mg Tablet for the treatment of prostate cancer.
Take it with or without food, preferably at the same time every day.
It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
If you are diabetic, monitor your blood glucose regularly while taking Zyluta 50mg Tablet.
Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not stop taking the medication without talking to your doctor first.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyluta 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. Can Zyluta 50mg Tablet cause infertility?
There is limited data to support that Zyluta 50mg Tablet causes infertility. Zyluta 50mg Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).
Q. What should I avoid while taking Zyluta 50mg Tablet?
Skin sensitivity has been observed in some patients while taking Zyluta 50mg Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Zyluta 50mg Tablet.
Q. Is Zyluta 50mg Tablet a form of chemotherapy?
No, Zyluta 50mg Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Zyluta 50mg Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.
Q. Does Zyluta 50mg Tablet cause hair loss?
Yes, Zyluta 50mg Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.
