Manufacturer: Zydus Cadila
Salt Composition : Nicorandil(5mg)
Zynicor 5 Tablet may be taken with or without food. It should be swallowed whole with water. Take this medicine regularly and at about the same time(s) each day. Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working. Do not stop taking it without talking to our doctor as sudden withdrawal may cause your chest pain to come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, exercising regularly, and managing stress.
The most common side effect of this medicine is headache, especially during the first few days of treatment. This usually improves within a week. However, drinking plenty of fluids and avoiding alcohol may help. Other common side effects include dizziness or weakness, nausea, and flushing (sense of warmth in the face, ears, neck, and trunk). Talk to your doctor if these bother you or do not go away.
Zynicor 5 Tablet may not be suitable for some people. Inform your doctor if you have a history of low blood pressure or heart failure. Also let your doctor know about all other medications that you are using as some may affect, or be affected by this medicine. You should not take any medicines for erectile dysfunction with this medicine. Zynicor 5 Tablet is not usually recommended during pregnancy or breastfeeding.
Zynicor 5 Tablet is a vasodilator. It works by reducing the workload of the heart. As a result, heart muscle does not need as much blood and oxygen supply. This reduces the frequency and severity of angina attacks.
Nicorandil pharmacokinetics are linear from 5 mg to 40 mg. After oral administration, nicorandil is absorbed rapidly and completely from the gastrointestinal tract, independent from food intake. The absolute bioavailability is about 75%. There is no significant hepatic first pass effect.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zynicor
Headache
Nausea
Vomiting
Weakness
Dizziness
Flushing (sense of warmth in the face, ears, neck and trunk)
ever had an allergic reaction to nicorandil or any other medicine.
low blood pressure (hypotension)
a problem with fluid build-up in the lungs (pulmonary oedema)
recently had a heart attack or been told you have heart failure.
Zynicor 5 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is unsafe to consume alcohol with Zynicor 5 Tablet.
Information regarding the use of Zynicor 5 Tablet during breastfeeding is not available. Please consult your doctor.
Nicorandil is indicated in adults for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or have a contraindication or intolerance to first-line antianginal therapies (such as beta-blockers and/or calcium antagonists).
Nicorandil may increase the hypotensive activities of Acebutolol. The therapeutic efficacy of Nicorandil can be decreased when used in combination with Aceclofenac. The therapeutic efficacy of Nicorandil can be decreased when used in combination with Acemetacin.
Do not chew, crush or break it. Zynicor 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Zynicor 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You must continue to take it as advised, usually for a long time.
Zynicor 5 Tablet may cause headaches. Drink plenty of water and take a suitable painkiller. Inform your doctor if it does not go away.
Zynicor 5 Tablet may cause dizziness or sleepiness. Do not drive or do anything which requires concentration until you know how it affects you.
Do not consume alcohol while taking Zynicor 5 Tablet as that may cause increased dizziness.
Do not take medications like sildenafil or tadalafil (prescribed for erectile dysfunction) while on treatment with Zynicor 5 Tablet as it may cause low blood pressure.
Inform your doctor if you notice any bleeding from the anal passage, blood in vomit or black stools.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zynicor 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
Q. What class of drug is Zynicor 5 Tablet and what is it used for?
Zynicor 5 Tablet belongs to a class of medicines known as “potassium channel openers”. It helps in the removal of potassium from the walls of arteries resulting in the widening of the arteries. This decreases the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta-blockers, calcium channel antagonist) meant for angina.
Q. Can I stop taking Zynicor 5 Tablet?
No, you should not stop taking Zynicor 5 Tablet without speaking to your doctor first. If you stop Zynicor 5 Tablet suddenly, your anginal pain may recur. Talk to your doctor if you are experiencing any side effects.
Q. How long does it take Zynicor 5 Tablet to start working?
Zynicor 5 Tablet starts working after about an hour of taking the medicine, but full benefits may be seen only after 4 to 5 days.
Q. For how long do I need to continue Zynicor 5 Tablet?
Continue taking your medicine for as long as your doctor tells you. Zynicor 5 Tablet is generally prescribed for a long term. You may even need to take it for the rest of your life.
