Manufacturer: Zydus Cadila
Salt Composition : Hydroxychloroquine(400mg)
ZY-Q 400 Tablet should be taken with food. This will prevent you from getting an upset stomach upset. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better.
The common side effects of this medicine include blurred vision and increased sensitivity to light. It may even change the color of your eyes. Consult with your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.
To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Also, tell your doctor about all the other medicines you are taking. Your doctor may recommend regular eye tests to check your vision while on this medication. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.
Chloroquine and hydroxychloroquine increase pH within intracellular vacuoles and alter processes such as protein degradation by acidic hydrolases in the lysosome, assembly of macromolecules in the endosomes, and posttranslation modification of proteins in the Golgi apparatus.
Oral hydroxychloroquine has an absorption half life of 3-4 hours. A 200mg oral dose of hydroxychloroquine has a half life of 537 hours or 22.4 days in blood, and 2963 hours or 123.5 days in plasma. A 155mg intravenous dose has a half life of 40 days. The clearance of hydroxychloroquine is 96mL/min.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of ZY-Q
Blurred vision
Headache
Diarrhea
Abdominal pain
Vomiting
Nausea
Decreased appetite
Skin rash
Itching
Affect lability
Blood or bone marrow problems or.
Eye or vision problems or.
Muscle problems or.
Nerve problems or.
Porphyria (blood disorder) or.
Psoriasis (skin disease) or.
Stomach or bowel problems–Use with caution.
ZY-Q 400 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with ZY-Q 400 Tablet. Please consult your doctor.
ZY-Q 400 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults.
Hydroxychloroquine is used to treat conditions like RA, lupus, and malaria. It can interact with heart rhythm medications, diabetes medications, seizure medications, and digoxin. And it shouldn't be taken with remdesivir because it can make remdesivir less effective.
Do not chew, crush or break it. ZY-Q 400 Tablet is to be taken with food.
Store below 30°C
If you miss a dose of ZY-Q 400 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
You have been prescribed ZY-Q 400 Tablet for the treatment of autoimmune conditions such as rheumatoid arthritis or systemic lupus erythematosus.
Take it with food to avoid an upset stomach.
It can take 8-12 weeks for ZY-Q 400 Tablet to work. Keep taking it as prescribed.
Do not take medicines that neutralise stomach acids (antacids) four hours before and after taking ZY-Q 400 Tablet as they can stop the medicine from being absorbed properly from your gut.
Have regular eye tests done while taking this medicine. Stop taking it and inform your doctor immediately if you notice any changes in your vision.
It can cause lowering of blood glucose level. Inform your doctor if you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ZY-Q 400 Tablet is to be taken with food.
Q. Is ZY-Q 400 Tablet effective against novel coronavirus infection?
ZY-Q 400 Tablet is currently under study in various clinical trials (research studies in human beings) for the prevention of novel coronavirus infection and treatment of patients with COVID-19 (the illness caused by the novel coronavirus). This medicine has shown some activity against the novel coronavirus in laboratory studies (in vitro studies). However, further evidence is required to conclude that ZY-Q 400 Tablet is effective against the novel coronavirus.
Q. Can ZY-Q 400 Tablet be used for the prophylaxis of the novel coronavirus infection?
The national task force for COVID-19 (constituted by ICMR) has recommended the use of ZY-Q 400 Tablet for prevention of novel coronavirus infection ONLY in certain high-risk populations (ie people at high risk of exposure to the virus) or emergency situations. It can be used for prophylaxis in case of asymptomatic healthcare workers involved in the care of suspected or confirmed cases of COVID-19 and asymptomatic household contacts of laboratory-confirmed cases.
Q. Do we need to maintain a stock of ZY-Q 400 Tablet?
No, we do not have to maintain a stock of ZY-Q 400 Tablet. If you suspect that you have contracted the novel coronavirus infection, consult a doctor immediately and strictly follow their advice. Do not self-administer ZY-Q 400 Tablet. Keep in mind that this medicine needs to be taken only if prescribed by a registered medical practitioner.
Q. What is the recommended dose for preventing coronavirus?
ZY-Q 400 Tablet is only recommended for preventing coronavirus infection in certain high-risk groups or emergency situations. It should strictly be taken as per the dose, frequency, and duration prescribed by your doctor.
