Manufacturer: Cipla Ltd
Salt Composition : Allopurinol(100mg)
Strip of 10 Tablet
(Inclusive of all taxes)
Zyrik 100 Tablet should be taken after food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because more crystals form in your joints and kidneys. You can help yourself by making some changes to your diet and drinking plenty of fluids.
Some of the common side effects of this medicine are rash, nausea, and diarrhea. Your doctor may help with ways to reduce or prevent these symptoms. Some people may get a severe allergic reaction that needs urgent medical attention. Talk to your doctor straight away if you get symptoms of liver disease including nausea that does not stop, yellowing skin or eyes, or dark urine.
To make sure it is safe for you, before taking this medicine, let your doctor know if you have or have had heart failure, heart problems, stroke, kidney or liver disease, or thyroid problems. Do not use this medicine if you are pregnant or breastfeeding. Check with your doctor. You will be asked for regular blood tests to check that your liver is working properly.
Zyrik 100 Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.
The pharmacokinetic parameters of allopurinol after oral dosage include oral bioavailability of 79 +/- 20% (mean +/- SD), an elimination half-life (t((1/2))) of 1.2 +/- 0.3 hours, apparent oral clearance (CL/F) of 15.8 +/- 5.2 mL/min/kg and an apparent volume of distribution after oral administration (V(d)/F) of 1.31 ...
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zyrik
Skin rash
Diarrhea
Nausea
General Information. ...
Serious rash. ...
Renal disease, renal failure, renal impairment. ...
Hepatic disease, hepatotoxicity. ...
Anticoagulant therapy, bone marrow suppression. ...
Driving or operating machinery. ...
Pregnancy. ...
Breast-feeding.
Zyrik 100 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Caution is advised when consuming alcohol with Zyrik 100 Tablet. Please consult your doctor.
Zyrik 100 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Allopurinol is FDA approved for the following indications: Gout. Prevention of tumor lysis syndrome. Prevention of recurrent calcium nephrolithiasis in patients with hyperuricosuria.
aluminum hydroxide.
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dichlorphenamide.
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mercaptopurine.
Do not chew, crush or break it. Zyrik 100 Tablet is to be taken with food.
Store below 30°C
If you miss a dose of Zyrik 100 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Your doctor has prescribed Zyrik 100 Tablet to reduce episodes of gout attack.
Take Zyrik 100 Tablet with food to avoid stomach upset.
Take plenty of fluids (2-3 litres) daily while on Zyrik 100 Tablet.
Notify your doctor if you develop a rash. This could be a sign of allergy and should go away on discontinuing Zyrik 100 Tablet.
When you first start taking this medicine, you might have more gout attacks. Do not stop Zyrik 100 Tablet on having an acute attack of gout as that could make an attack worse.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zyrik 100 Tablet is to be taken with food.
Q. What is the best time of the day to take Zyrik 100 Tablet?
Zyrik 100 Tablet can be taken at anytime of the day but preferably should be taken at the same time each day so that you remember to take it. It is usually prescribed once daily and should be taken after meals. If the dose exceeds 300 mg or if your stomach is upset, you can take it in divided doses as advised by your doctor.
Q. Why do I still get gout while taking Zyrik 100 Tablet?
If you have started taking Zyrik 100 Tablet, you may experience an increase in attacks of gout (severe pain, swelling, and redness). However, these attacks usually become shorter and less severe after several months of therapy. The possible reason for increased attacks could be gradual breakdown of uric acid crystals, causing fluctuations in uric acid levels in the blood. To prevent such painful events, your doctor may advise to take colchicine with Zyrik 100 Tablet, as it can suppress the gouty attacks.
Q. How long does it take for Zyrik 100 Tablet to lower uric acid levels?
It may take several months before you start feeling better or notice any significant reduction in attacks of gout (severe pain, swelling, and redness). Initially after starting Zyrik 100 Tablet you may experience gouty attacks. Continue taking Zyrik 100 Tablet even if you do not experience any considerable relief from the attacks. Do not stop taking Zyrik 100 Tablet without consulting your doctor. Your doctor will prescribe you another medicine along with Zyrik 100 Tablet to prevent the initial attacks. It may take up to years for the body to completely get rid of all uric acid crystals.
Q. What if I take alcohol while taking Zyrik 100 Tablet?
You should refrain yourself from consuming alcohol while taking Zyrik 100 Tablet as this could make your condition worse. Also, you should avoid all foods that are rich source of proteins as it will help to prevent attacks of gout. Consult your doctor for a detailed list of food items which need to be avoided. It is also recommended that you drink at least 8 glasses of water or other fluids while taking Zyrik 100 Tablet, unless your doctor has advised otherwise.
