Manufacturer: Zydus Cadila
Salt Composition : Recombinant Human Erythropoietin Alfa(3000IU)
Zyrop 3000IU Injection is given by injection either under the skin or into a vein which will be decided by your doctor. Usually, the injections are given by a nurse or doctor. The dose depends on your body weight and the cause of your anemia. Iron supplements both before and during treatment may make this treatment more effective. Zyrop 3000IU Injection needs to be stored in a fridge but used at room temperature.
The most common side effects of taking this medicine include nausea, vomiting, fever, and increased blood pressure. It may also cause flu-like symptoms such as headache, tiredness, dizziness and aches and pains. These side effects are most common at the start of treatment but if they persist your doctor may be able to suggest ways of preventing or reducing them. Tell your doctor straight away if you get any serious side effects, including seizures (fits). Sometimes this medicine can cause serious blood clots that need urgent medical attention.
Before using Zyrop 3000IU Injection you should tell your doctor if you have uncontrolled high blood pressure, heart disease, or gout (disease of joint pain). You should also tell him/her what other medicines you are taking in case they affect this treatment. Your blood pressure should be checked often during this treatment by you or your doctor. You may also need other regular medical tests to be sure this medicine is not causing harmful effects. It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.
Epoetin alfa promotes the formation of red blood cells in the bone marrow, which increases the red blood cell count in the body.
The bioavailability of epoetin administered intraperitoneally in dialysis fluid is about 3 to 8%, but this may be increased by injecting the drug into a dry peritoneal cavity. Subcutaneous administration results in peak concentrations at about 18 hours which are 5 to 10% of those found after the same intravenous dose.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rpo
High blood pressure
Nausea
Vomiting
Fever
Rash
Joint pain
Headache
Insomnia (difficulty in sleeping)
Chills
Cough
Bone pain
Muscle spasm
Dizziness
Vascular occlusion
Injection site irritation
Stomatitis (Inflammation of the mouth)
Weight loss
Decreased white blood cell count (lymphocytes)
Increased glucose level in blood
Blood clot in the blood vessels
ERYTHROPOIETIN ALFA, HUMAN RECOMBINANT should not be used in patients with high blood pressure and fits disorder.
Zyrop 3000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Zyrop 3000IU Injection. Please consult your doctor.
Zyrop 3000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Epoetin alfa injection products are used to treat anemia (a lower than normal number of red blood cells) in people with chronic kidney failure (condition in which the kidneys slowly and permanently stop working over a period of time).
ERYTHROPOIETIN ALFA, HUMAN RECOMBINANT may have interaction with medicines used after kidney transplant (cyclosporine), other medicines for cancer and anemia (lenalidomide), medicines used for skin disease and cancer (thalidomide), anticancer (pomalidomide).
Kindly do not self administer.
Store in a refrigerator (2 - 8°C). Do not freeze.
If you miss a dose of Zyrop 3000IU Injection, please consult your doctor.
Consult a doctor before taking any medicines.
Zyrop 3000IU Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
It is given as a single injection under your skin.
Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
Stop taking Zyrop 3000IU Injection and inform your doctor if you develop shortness of breath or skin rash.
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Q. How should Zyrop 3000IU Injection be stored?
In the hospital, pre-filled syringes are stored unopened in a refrigerator between 2 and 8 ℃. If you are using this medicine at home, it is important that the pre-filled syringe is stored in your refrigerator. Do not store it in the freezer. Allow the pre-filled syringe to reach room temperature prior to using it. This usually takes between 15 and 30 minutes. Zyrop 3000IU Injection pre-filled syringes that are being used or about to be used can be kept at room temperature (not above 25°C) for a maximum single period of 7 days. Keep these pre-filled syringes away from children and protected from light.
Q. What to do if you use too much Zyrop 3000IU Injection?
Tell the doctor or nurse immediately if you think too much Zyrop 3000IU Injection has been injected.
Q. When should Zyrop 3000IU Injection not be used?
Zyrop 3000IU Injection should not be used if the solution is clouded or you can see particles floating in it or if the medicine has expired. Refer to the expiry date on the label. You should also not use the medicine if you know or think that it may have been accidentally frozen or if there has been a refrigerator failure.
Q. Can Zyrop 3000IU Injection be used in children?
Yes, Zyrop 3000IU Injection is used to treat anemia caused due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Zyrop 3000IU Injection and side effects seen in children are similar to adults.
