Chagas Disease

During the acute phase of infection, parasites may be seen circulating in the blood. The diagnosis of Chagas disease can be made by observation of the parasite in a blood smear by microscopic examination. A thick and thin blood smear are made and stained for visualization of parasites.

Diagnosis of chronic Chagas disease is made after consideration of the patient’s clinical findings, as well as by the likelihood of being infected, such as having lived in a country where Chagas disease is common. Diagnosis is generally made by testing for parasite specific antibodies.

Treatment for Chagas disease focuses on killing the parasite and managing signs and symptoms.

During the acute phase of Chagas disease, the prescription medications benznidazole and nifurtimox (Lampit) may be of benefit. Both drugs are available in the regions most affected by Chagas disease. In the United States, however, the drugs can be obtained only through the Centers for Disease Control and Prevention.

Once Chagas disease reaches the chronic phase, medications won't cure the disease. But, the drugs may be offered to people younger than age 50 because they may help slow the progression of the disease and its most serious complications.

Additional treatment depends on the specific signs and symptoms:

Heart-related complications. Treatment may include medications, a pacemaker or other devices to control your heart rhythm, surgery, or even a heart transplant.

Digestive-related complications. Treatment may include diet changes, medications, corticosteroids or, in severe cases, surgery.