Tertiary parathyroid

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Diagnosis

Tertiary hyperparathyroidism is characterized by excessive secretion of PTH after longstanding secondary hyperparathyroidism, in which hypercalcemia has ensued. Tertiary hyperparathyroidism typically occurs in men and women with chronic kidney disease usually after kidney transplant.

Blood tests will show raised calcium and parathyroid hormone levels. Phosphate levels can be variable, dependent on kidney function.

Treatment

The high blood calcium levels may be controlled with a drug called Cinacalcet. However, the definitive treatment is surgery, which involves partial or total removal of the parathyroid glands (parathyroidectomy).