Diphtheria

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Diagnosis

Doctors may suspect diphtheria in a sick child who has a sore throat with a gray membrane covering the tonsils and throat. Growth of C. diphtheriae in a lab culture of material from the throat membrane confirms the diagnosis. Doctors can also take a tissue sample from an infected wound and have it tested in a lab to check for the type of diphtheria that affects the skin (cutaneous diphtheria).


If a doctor suspects diphtheria, treatment begins immediately, even before the results of bacterial tests are available.

Treatment

Diphtheria is a serious illness. Doctors treat it immediately and aggressively. Doctors first ensure that the airway isn't blocked or reduced. In some cases, they may need to place a breathing tube in the throat to keep the airway open until the airway is less inflamed. Treatments include:


Antibiotics. Antibiotics, such as penicillin or erythromycin, help kill bacteria in the body, clearing up infections. Antibiotics lessen the time that someone with diphtheria is contagious.

An antitoxin. If a doctor suspects diphtheria, he or she will request a medication that counteracts the diphtheria toxin in the body. This medication comes from the Centers for Disease Control and Prevention. Called an antitoxin, this drug is injected into a vein or muscle.


Before giving an antitoxin, doctors may perform skin allergy tests. These are done to make sure that the infected person doesn't have an allergy to the antitoxin. If someone has an allergy, the doctor will likely recommend that he or she not get the antitoxin.


Children and adults who have diphtheria often need to be in the hospital for treatment. They may be isolated in an intensive care unit because diphtheria can spread easily to anyone not vaccinated against the disease.